Complex Mixtures

Mixtures of many components in inexact proportions, usually natural, such as PLANT EXTRACTS; VENOMS; and MANURE. These are distinguished from DRUG COMBINATIONS which have only a few components in definite proportions.

Also Known As:

Networked: 485 relevant articles (22 outcomes, 59 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	National Toxicology Program: 5 articles (09/2006 - 01/2006)
2.	Chung, Jing-Gung: 4 articles (05/2011 - 07/2007)
3.	Kuete, Victor: 3 articles (01/2015 - 02/2007)
4.	Murugan, Kadarkarai: 3 articles (03/2013 - 11/2012)
5.	Quetin-Leclercq, Joëlle: 3 articles (09/2011 - 04/2009)
6.	Beng, Véronique Penlap: 3 articles (03/2010 - 02/2007)
7.	Kuo, Chao-Lin: 3 articles (03/2008 - 07/2007)
8.	Su, Chin-Cheng: 3 articles (03/2008 - 07/2007)
9.	Hsu, Shu-Chun: 3 articles (03/2008 - 07/2007)
10.	Yenesew, Abiy: 2 articles (12/2015 - 11/2015)

Related Diseases

1.	Bites and Stings (Sting) 09/01/2013 - "Pharmacological investigation and spectral characterization of bioactive compounds from crude extracts of sting ray, Dasyatis jenkinsii (Annandale, 1909)." 02/01/2015 - "In this observation, these two plant crude extracts gave protection against mosquito bites; also, the repellent activity is dependent on the strength of the plant extracts. " 03/01/2013 - "In this observation, this plant crude extracts gave protection against mosquito bites without any allergic reaction to the test person, and also, the repellent activity is dependent on the strength of the plant extracts. " 02/01/2013 - "In this observation, these three plant crude extracts gave protection against mosquito bites without any allergic reaction to the test person, and also, the repellent activity is dependent on the strength of the plant extracts. " 11/01/2012 - "In this observation, this plant crude extracts gave protection against mosquito bites without any allergic reaction to the test person, and also, the repellent activity is dependent on the strength of the plant extracts. "
2.	Hypersensitivity (Allergy) 01/01/2008 - "To test the allergenic potency, crude extracts of these strains were subjected to intra-dermal allergy test and subsequent leukocyte counts, which revealed their allergenic nature. " 07/01/1994 - "Crude extracts from the various cultivars were tested in 6 atopic patients with confirmed allergy to date pollen in order to determine any differences or similarities in the antigenic and allergenic properties of these cultivars. " 06/01/1994 - "Mice immunized orally with the live vaccine did not show hypersensitivity to either LPS or crude extracts. " 03/01/2008 - "The diagnosis and immunotherapy currently applied to allergic diseases involve the use of crude extracts of the allergen source without defining the allergy-eliciting molecule(s). " 01/01/2006 - "To date, substitution of complex extracts presently used in the diagnosis of fungal allergy by single, perfectly standardized components seems feasible in contrast to specific immunotherapy which is still not developed. "
3.	Neoplasms (Cancer) 01/01/1979 - "Preliminary clinical trials with crude extracts have provided promising results in immunodeficient and cancer patients. " 01/01/2010 - "Crude extracts of this plant have been found to be cytotoxic to human cancer cell lines and protective against chemically-induced hepatocarcinogenesis in rats. " 11/01/1994 - "This review is based on literature data pertaining to the use of single agents or complex mixtures that have been shown to offer protection against mammary cancer in rodents. " 01/01/2015 - "Apoptotic studies in the cells of A498 (cancer) and MCF-10A (normal human epithelial) exposed to crude extracts and TLC fractions revealed no significant impact on MCF-10A cells emphasizing its importance in the development of anticancer drug. " 01/01/2014 - "In pharmacological studies, crude extracts of Astragalus, as well as isolated constituents showed anti-inflammatory, immunostimulant, antioxidative, anti-cancer, antidiabetic, cardioprotective, hepatoprotective, and antiviral activities. "
4.	Breast Neoplasms (Breast Cancer) 03/01/2010 - "Crude extracts of the tree were found to be highly effective against ovarian and breast cancer lines tested." 04/01/2012 - "Whether or not the weight of evidence eventually establishes any causal link of complex mixtures of environmental oestrogenic chemicals with breast cancer, the presence of so many oestrogenic chemicals in the breast must influence resulting oestrogenic responses, and the impact of this additional oestrogenic burden needs to be taken into account in future studies on growth regulation of human breast cancer cells. " 04/01/2011 - "Although OCs has been tested individually for their capacity to induce breast cancer cell proliferation, few studies examined the effect of complex mixtures that comprise compounds frequently detected in the serum of women. " 09/01/2015 - "This methodology developed for breast cancer detection can be considered a general strategy that is applicable to various pathologies and other chemical analytical cases where complex mixtures have to be resolved in their constitutive components. " 01/01/2014 - "Cytotoxic Activities against Breast Cancer Cells of Local Justicia gendarussa Crude Extracts."
5.	Multiple Sclerosis 02/16/2011 - "Although the effect of crude extracts of Cannabis sativa here reported need to be further investigated to define the exact therapeutic target of each cannabinoid, it may represent a possible therapeutic approach for the management of the multiple sclerosis." 02/16/2011 - "The aim of the present study was to investigate the efficacy of crude extracts of Cannabis sativa on motor symptoms in the chronic relapsing experimental autoimmune encephalomyelitis (CREAE), a murine model of multiple sclerosis. "

Related Drugs and Biologics

1.	Plant Extracts
2.	Antigens
3.	Anti-Bacterial Agents (Antibiotics)
4.	Vitamins
5.	Peptides
6.	Insulin (Novolin)
7.	Polychlorinated Biphenyls (PCBs)
8.	chlorinated dibenzofurans
9.	Ethanol (Ethyl Alcohol)
10.	Enzymes

Related Therapies and Procedures

1.	Traditional Medicine (Folk Remedies)
2.	Immunotherapy
3.	Immunomodulation
4.	Lasers (Laser)
5.	Isogeneic Transplantation