Kanamycin

Antibiotic complex produced by Streptomyces kanamyceticus from Japanese soil. Comprises 3 components: kanamycin A, the major component, and kanamycins B and C, the minor components.

Also Known As:

Networked: 732 relevant articles (42 outcomes, 45 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Garneau-Tsodikova, Sylvie: 4 articles (11/2013 - 06/2011)
2.	Ohlemiller, Kevin K: 3 articles (08/2014 - 06/2010)
3.	Tsodikov, Oleg V: 3 articles (11/2013 - 06/2011)
4.	Chen, Wenjing: 3 articles (11/2013 - 06/2011)
5.	Goby, L: 3 articles (06/2012 - 12/2009)
6.	Guo, Wei-Wei: 2 articles (10/2015 - 07/2013)
7.	Yang, Shi-Ming: 2 articles (10/2015 - 07/2013)
8.	van Altena, R: 2 articles (09/2015 - 07/2002)
9.	Marchelletta, Ronald R: 2 articles (07/2015 - 12/2013)
10.	Gareau, Melanie G: 2 articles (07/2015 - 12/2013)

Related Diseases

1.	Infection 03/01/1984 - "Kanamycin alone was effective against the infection. " 11/01/1967 - "[Efficacy of kanamycin in surgical infection. " 09/30/1958 - "The efficacy of kanamycin in the treatment of surgical infections." 07/01/2010 - "To study the role of gC in EHV-4 infection, we constructed a gC-deletion mutant, WA79DeltagC, where the kanamycin resistant gene was inserted instead of the open reading frame encoding gC. " 01/01/1968 - "[Study of the sensitivity of polyresistant strains of microbial causative agents of purulent infections to kanamycin sulfate]."
2.	Wound Infection (Wound Infections) 01/01/1976 - "Kanamycin can be recommended as an effective and safe topical antibiotic to prevent wound infections in foot surgery." 12/01/1983 - "Adequate prophylaxis did not depend on the route of antimicrobial administration, but wound infection rates were increased following exclusion of kanamycin." 01/01/1976 - "The local use of kanamycin, a broad spectrum antibiotic, has been successful in preventing primary wound infections. " 03/01/1964 - "PREVENTION OF EXPERIMENTAL STAPHYLOCOCCAL WOUND INFECTIONS IN RABBITS WITH TOPICAL KANAMYCIN." 12/01/1983 - "A randomized double-blind trial was conducted in two phases to compare the efficacy of prophylactic oral and intravenous administration of kanamycin and metronidazole in preventing wound infection and other complications in patients undergoing colorectal surgery, and also to assess the need for inclusion of an aminoglycoside in the prophylactic regimen. "
3.	Wounds and Injuries (Trauma) 06/01/1996 - "A prospective, randomized double-blinded study compared using either 500 mg of intraperitoneal kanamycin or a saline control in 69 adult trauma patients requiring diagnostic peritoneal lavage was conducted over a 24-month period. " 06/01/1996 - "Intraperitoneal kanamycin given to trauma patients requiring diagnostic peritoneal lavage within the first three hours following injury reduces the incidence of infectious complications and shortens intensive care unit and hospital stay." 06/01/1984 - "In 48.2 per cent of the patients, this was accompanied by development of resistance to kanamycin in the whole microbial population of the wound. " 06/01/1984 - "The treatment with kanamycin alone resulted in a 2.6-fold increase in the number of the antibiotic-resistant variants in the microbial populations of the wounds. " 06/01/1984 - "As compared to the patients treated with kanamycin alone, the rate of the wound size decrease in such patients was 2 times higher. "
4.	Bacteriuria 03/01/1978 - "Prophylactic kanamycin did not protect the patient with carcinoma of the prostate from bacteriuria. " 03/01/1978 - "In the non-risk patient prophylactic kanamycin had no beneficial influence on the incidence of bacteriuria, fever or length of hospitalization. " 12/01/2010 - "Of four controlled studies using neomycin or kanamycin, two demonstrated a significant reduction in bacteriuria, whilst two other trials did not. " 09/01/1968 - "Treatment of postpartum bacteriuria with a combination of kanamycin and penicillin." 10/01/1979 - "The value of kanamycin-colistin bladder instillations in reducing bacteriuria during intermittent catheterisation of patients with acute spinal cord injury."
5.	Bacillary Dysentery (Shigellosis) 06/01/1963 - "[STUDIES ON KANAMYCIN THERAPY OF BACILLARY DYSENTERY (INCLUDING RESISTANT BACILLARY DYSENTERY)]." 03/01/1973 - "[Therapeutic use of bacillary dysentery and related diseases: with special reference to the comparison with kanamycin by a double blind method]." 02/01/1959 - "Kanamycin in bacillary dysentery." 04/01/1983 - "[Comparison of clinical efficacy of pipemidic acid (PPA) and kanamycin (KM) in bacillary dysentery by double blind method]." 07/01/1980 - "[Comparison of clinical efficacy of fosfomycin (FOM) and kanamycin (KM) in bacillary dysentery by double blind method (author's transl)]."

Related Drugs and Biologics

1.	Gentamicins (Gentamicin)
2.	Anti-Bacterial Agents (Antibiotics)
3.	Streptomycin (Streptomycin Sulfate)
4.	Ampicillin (Omnipen)
5.	Amikacin (A.M.K)
6.	Rifampin (Rifampicin)
7.	Ethambutol (Myambutol)
8.	Tobramycin (Nebcin)
9.	Ethionamide (Trecator-SC)
10.	Cycloserine (Seromycin)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Gastric Bypass (Roux-en-Y Gastric Bypass)
3.	Intravesical Administration
4.	Prostatectomy (Retropubic Prostatectomy)
5.	Colectomy