Bipolar and Related Disorders

These disorders are related to both SCHIZOPHRENIA SPECTRUM AND OTHER PSYCHOTIC DISORDERS and DEPRESSIVE DISORDER in terms of symptomatology, family history, and genetics. (DSM-5).

Networked: 10 relevant articles (0 outcomes, 2 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Schizophrenia (Dementia Praecox)
2.	Mania (Manias)
3.	Neurodevelopmental Disorders
4.	Premenstrual Dysphoric Disorder
5.	Schizophrenia Spectrum and Other Psychotic Disorders

Experts

1.	Bice, Collette: 1 article (01/2021)
2.	Holmes, Traci: 1 article (01/2021)
3.	Ivleva, Elena: 1 article (01/2021)
4.	McArdle, Meagan: 1 article (01/2021)
5.	McNutt, Markey: 1 article (01/2021)
6.	Nakamura, Alyson: 1 article (01/2021)
7.	Palka, Jayme: 1 article (01/2021)
8.	Patel, Zena: 1 article (01/2021)
9.	Sherwood Brown, E: 1 article (01/2021)
10.	Tipton, Shane: 1 article (01/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Bipolar and Related Disorders:

1.	Antipsychotic Agents (Antipsychotics)IBA 08/01/2011 - "Future observational studies should consider current clinical status as an important factor in determining propensity to receive antipsychotics or other short-term treatments for bipolar and related disorders." 07/20/2019 - "Age (hazard ratio [HR] = 1.04, P < 0.001), diagnosis of schizophrenia (HR = 1.99, P < 0.001), antipsychotic dosage (up to 100 mg/day chlorpromazine equivalent; HR = 1.65, P < 0.01), and comorbid bipolar and related disorders (HR = 1.39, P < 0.01) were significantly associated with an increased risk of TD. "
2.	Anticonvulsants (Antiepileptic Drugs)IBA 01/01/2001 - "The use of anticonvulsants is expanding in the treatment of bipolar and related disorders. " 10/15/2012 - "Some drugs developed as anticonvulsants (notably, valproate and lamotrigine) have therapeutic effects in bipolar and related disorders. "
3.	Therapeutic UsesIBA 10/15/2012 - "Some drugs developed as anticonvulsants (notably, valproate and lamotrigine) have therapeutic effects in bipolar and related disorders. "
4.	Risperidone (Risperdal Consta)FDA LinkGeneric 01/01/2020 - "For risperidone, attention-deficit/hyperactivity disorder (25.4%), disruptive, impulse-control, and conduct disorders (17.1%), and bipolar and related disorders (14.2%) were more commonly reported as clinical indications. "
5.	Ondansetron (Zofran)FDA LinkGeneric 01/01/2021 - "A randomized, double-blind, placebo-controlled proof-of-concept study of ondansetron for bipolar and related disorders and alcohol use disorder."
6.	Valproic Acid (Depakote)FDA LinkGeneric 10/15/2012 - "Some drugs developed as anticonvulsants (notably, valproate and lamotrigine) have therapeutic effects in bipolar and related disorders. "
7.	Chlorpromazine (Thorazine)FDA Link 07/20/2019 - "Age (hazard ratio [HR] = 1.04, P < 0.001), diagnosis of schizophrenia (HR = 1.99, P < 0.001), antipsychotic dosage (up to 100 mg/day chlorpromazine equivalent; HR = 1.65, P < 0.01), and comorbid bipolar and related disorders (HR = 1.39, P < 0.01) were significantly associated with an increased risk of TD. "
8.	Antidepressive Agents (Antidepressants)IBA 01/01/2018 - "The authors present a narrative review from the diagnostic and nosologic viewpoints of mood disorders (bipolar and depressive ones) by revisiting the revision from the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders, Text Revision to DSM-5, including the following: the separation of the bipolar and depressive sections; the addition of increased energy and continuation of symptoms to the hypo/manic criteria; the elimination of mixed episodes; the creation of new categories and specifiers ("other specified bipolar and related disorder", "disruptive mood dysregulation disorder", "with anxious distress", "with mixed features", "with peripartum onset"); the categorization of hypo/manic episodes during antidepressant treatment into bipolar disorder; the elimination of the "bereavement exclusion"; the ambiguous separation between bipolar I and II; the insufficient distinction between "other specified bipolar and related disorders" and major depressive disorder; the differentiation regarding borderline personality disorder; agitation; premenstrual dysphoric disorder; and society and psychiatry. "
9.	Lamotrigine (Lamictal)FDA LinkGeneric 10/15/2012 - "Some drugs developed as anticonvulsants (notably, valproate and lamotrigine) have therapeutic effects in bipolar and related disorders. "
10.	Member 11 Subfamily B ATP Binding Cassette TransporterIBA 09/01/2016 - "Bipolar and Related Disorders Induced by Sodium 4-Phenylbutyrate in a Male Adolescent with Bile Salt Export Pump Deficiency Disease."

Therapies and Procedures

1.	Contraception (Birth Control) 01/01/2020 - "The aim of this study was to investigate impulsivity levels, contraception methods, and levels of planned pregnancies among women with bipolar and related disorders (WBD). "