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Wilms Tumor 3

Also Known As:

WT3

Networked: 14 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Infections
2.	Acute Erythroblastic Leukemia (Erythroleukemia)
3.	Reperfusion Injury
4.	Otitis Media
5.	Lung Neoplasms (Lung Cancer)

Experts

1.	Zabala, Mikel: 2 articles (12/2011 - 09/2008)
2.	Cao, Peng: 1 article (01/2022)
3.	Deng, Yu: 1 article (01/2022)
4.	Han, Peng: 1 article (01/2022)
5.	Hu, Shan: 1 article (01/2022)
6.	Kong, Kangle: 1 article (01/2022)
7.	Li, Fan: 1 article (01/2022)
8.	Li, Lequn: 1 article (01/2022)
9.	Yue, Jiaqi: 1 article (01/2022)
10.	Zhao, Bo: 1 article (01/2022)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Wilms Tumor 3:

1.	Lactic Acid (Lactate)FDA LinkGeneric 09/01/2008 - "For the NaHCO3- trial, peak blood lactate during recovery was greater after WT2 (p < 0.05) and tended to be greater after WT3 (p = 0.07), and ratings of perceived exertion were not influenced. "
2.	Growth Hormone (Somatotropin)IBA 09/01/1977 - "Six children aged 12-15 yr, deficient in endogenous growth hormone, were each treated, after a 7-day control period, for 7 days with 0.0168, 0.052, and 0.168 U/kg body wt3/4 human growth (hGH) (doses A, B, and C, respectively) in separate metabolic balance studies. "
3.	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 08/01/1993 - "The effect of cryopreservation on agonist-induced receptor activation in mammalian cells was investigated with the Cytosensor microphysiometer, a biosensor that monitors cellular metabolic activity by measuring changes in extracellular pH. In this study, two different cell types--nonadherent TF-1 cells (from a human erythroleukemia patient) and adherent WT3 cells (CHO-K1 cells transfected with the m1 muscarinic acetylcholine receptor)--were cryopreserved by freezing in a disposable cell capsule used in the microphysiometer. "
4.	Capsules (Microcapsules)IBA 08/01/1993 - "The effect of cryopreservation on agonist-induced receptor activation in mammalian cells was investigated with the Cytosensor microphysiometer, a biosensor that monitors cellular metabolic activity by measuring changes in extracellular pH. In this study, two different cell types--nonadherent TF-1 cells (from a human erythroleukemia patient) and adherent WT3 cells (CHO-K1 cells transfected with the m1 muscarinic acetylcholine receptor)--were cryopreserved by freezing in a disposable cell capsule used in the microphysiometer. "
5.	Bicarbonates (Hydrogen Carbonate)IBA 12/01/2011 - "MP WT1: 809 ± 113 vs. 812 ± 108 W; MP WT2: 799 ± 135 vs. 799 ± 124 W; MP WT3: 762 ± 165 vs. 782 ± 118 W (bicarbonate vs. placebo conditions, respectively)]. " 12/01/2011 - "Significant differences (p < 0.05) were observed in acid-base variables [pH before WT1: 7.47 ± 0.05 vs. 7.41 ± 0.03; [HCO(3) (-)] before WT1: 29.08 ± 2.27 vs. 22.85 ± 0.24 mmol L(-1) (bicarbonate vs. placebo conditions, respectively)], but there were not significant differences in performance variables between trials [PP WT1: 1,610 ± 373 vs. 1,599 ± 370 W; PP WT2: 1,548 ± 460 vs. 1,570 ± 428 W; PP WT3: 1,463 ± 361 vs. 1,519 ± 364 W. "
6.	AcidsIBA 12/01/2011 - "Significant differences (p < 0.05) were observed in acid-base variables [pH before WT1: 7.47 ± 0.05 vs. 7.41 ± 0.03; [HCO(3) (-)] before WT1: 29.08 ± 2.27 vs. 22.85 ± 0.24 mmol L(-1) (bicarbonate vs. placebo conditions, respectively)], but there were not significant differences in performance variables between trials [PP WT1: 1,610 ± 373 vs. 1,599 ± 370 W; PP WT2: 1,548 ± 460 vs. 1,570 ± 428 W; PP WT3: 1,463 ± 361 vs. 1,519 ± 364 W. "
7.	DNA (Deoxyribonucleic Acid)IBA 02/19/2021 - "DNA-DNA hybridization between strain SNU WT3 and other close relatives indicated the results of J. " 09/01/1999 - "SV40 DNA was identified in samples from 4 of 20 children (1 Wilms' tumor, 3 transplanted kidney samples). "
8.	Monoclonal AntibodiesIBA 03/01/2001 - "The effects of treatment with monoclonal antibodies against CD11a (WT1) and CD18 (WT3) at a dose of 0.8 mg/kg on uterine blood flow and IUGR were investigated. " 09/12/1994 - "We therefore investigated the roles of CD11a/CD18 (LFA-1) and ICAM-1 in cerebral ischemia-reperfusion injury by using monoclonal antibodies, WT1 (anti-CD11a), WT3 (anti-CD18), and 1A29 (anti-ICAM-1). "
9.	Capsid Proteins (Capsid Protein)IBA 06/01/2015 - "We show here that capsid proteins of Mad-1 and WT3 JCPyV can both engage LSTc as well as multiple sialylated gangliosides. "
10.	LeptinIBA 09/01/2019 - "Sows in WT1 group showed a significant positive effect on the plasma IGF-1 at breeding and weaning time in parity 2. Sows in AG3 group showed a higher plasma leptin at breeding, farrowing, and weaning in the parity 1, and at farrowing in parity 2. Sows in WT3 group showed a higher plasma leptin at breeding, farrowing, and weaning in the parities 1 and 2. Considering the insignificant longevity results, the most efficient time for gilts insemination can be at 220 d when their body weight is 140 kg or lower."

Therapies and Procedures

1.	Aftercare (After-Treatment) 04/01/1996 - "Inflammatory cell influx was slightly, but not significantly, greater after treatment of WT3 infection than after treatment of P-1 infection. "
2.	Therapeutics 03/01/2006 - "Despite all thermoregulatory control mechanisms of the body and the complex metabolic processes involved, WT3 therapy seems a valuable tool to re-establish normal body functions. " 03/01/2006 - "However, just as estrogen and progesterone are prescribed to regulate menstrual cycles in patients who have normal serum hormone levels, the WT3 therapy can be used to regulate metabolism despite normal serum thyroid hormone levels. "
3.	Lasers (Laser) 03/01/2001 - "Laser-Doppler flowmetry demonstrated that uterine hypoperfusion at 2 h after ischemia (blood flow, -51.7 +/- 1.2%; P < 0.01) was inhibited by WT1 and WT3 treatment. "