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polypeptide fucosyltransferase (GDP-fucose protein O-fucosyltransferase 1)

from CHO cells; attaches fucose through an O-glycosidic linkage to serine or theonine in EGF domains

Also Known As:

GDP-fucose protein O-fucosyltransferase 1; GDPfucose - polypeptide fucosyltransferase; Pofut1 protein, human

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Glycosyltransferases: 784
      - Hexosyltransferases
        Fucosyltransferases: 329
        polypeptide fucosyltransferase: 1

Experts

1.	Haroutunian, Vahram: 1 article (01/2017)
2.	Meador-Woodruff, James H: 1 article (01/2017)
3.	Mueller, Toni M: 1 article (01/2017)
4.	Yates, Stefani D: 1 article (01/2017)

Related Diseases

1.

Schizophrenia (Dementia Praecox)

01/01/2017 - "Building on prior reports of glycosylation abnormalities and evidence of dysregulated glycosylation enzyme expression in schizophrenia, we examined the protein expression of 5 key fucose-modifying enzymes: GDP-fucose:protein O-fucosyltransferase 1 (POFUT1), GDP-fucose:protein O-fucosyltransferase 2 (POFUT2), fucosyltransferase 8 (FUT8), fucosyltransferase 11 (FUT11), and plasma α-l-fucosidase (FUCA2) in postmortem superior temporal gyrus of schizophrenia (N=16) and comparison (N=14) subjects. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Guanosine Diphosphate Fucose (GDP Fucose)
3.	Fucosyltransferases
4.	alpha-L-Fucosidase (Fucosidase)
5.	Fucose
6.	Enzymes
7.	Galactoside 2-alpha-L-fucosyltransferase (Fucosyltransferase 2)