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aethiopinone

structure in first source

Networked: 5 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Naphthoquinones: 418
        aethiopinone: 5
- Quinones: 434
  - Naphthoquinones: 418
    - aethiopinone: 5
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Naphthoquinones: 418
      - aethiopinone: 5

Experts

1.	De Tommasi, Nunziatina: 3 articles (01/2020 - 01/2018)
2.	Leone, Antonietta: 3 articles (01/2020 - 01/2018)
3.	Alfieri, Mariaevelina: 2 articles (01/2020 - 01/2018)
4.	Vaccaro, Maria Carmela: 2 articles (01/2020 - 01/2018)
5.	Goossens, Alain: 1 article (01/2020)
6.	Moses, Tessa: 1 article (01/2020)
7.	Malafronte, Nicola: 1 article (08/2019)
8.	Ocampo Bernal, Vivian: 1 article (08/2019)
9.	Vaccaro, Mariacarmela: 1 article (08/2019)
10.	Ambrosone, Alfredo: 1 article (01/2018)

Related Diseases

1.	Neoplasms (Cancer) 07/01/2006 - "sclarea diterpenoids aethiopinone and salvipisone may be useful in the treatment of human cancers, especially in the case of drug resistance."
2.	Melanoma (Melanoma, Malignant) 01/01/2018 - "Interestingly, in the best performing HR lines overexpressing the AtWRKY40 TF induced a significant 4-fold increase in the final yield of aethiopinone, for which we have reported an interesting anti-proliferative activity against resistant melanoma cells. " 01/01/2017 - "We have shown that aethiopinone, an abietane diterpene synthesized in Salvia sclarea roots is cytotoxic and induces apoptosis in human melanoma cells. " 01/01/2020 - "We have shown that aethiopinone has promising cytotoxic activity against several human tumor cell lines, including the breast adenocarcinoma MCF7, HeLa, epithelial carcinoma, prostate adenocarcinoma PC3, and human melanoma A375. " 08/01/2019 - "We have recently shown that aethiopinone, an o-naphto-quinone diterpene, produced in the roots of different Salvia species, is selectively cytotoxic against the A375 melanoma cell line. "
3.	Leukemia 07/01/2006 - "Salvipisone and aethiopinone showed relatively high cytotoxicity against HL-60 and NALM-6 leukemia cells (IC50 range 0.6-7.7 microg/ mL which is equal to 2.0-24.7 microM), whereas 1-oxoaethiopinone and ferruginol were less active in this regard. "
4.	Carcinoma (Carcinomatosis) 01/01/2020 - "We have shown that aethiopinone has promising cytotoxic activity against several human tumor cell lines, including the breast adenocarcinoma MCF7, HeLa, epithelial carcinoma, prostate adenocarcinoma PC3, and human melanoma A375. "
5.	Adenocarcinoma 01/01/2020 - "We have shown that aethiopinone has promising cytotoxic activity against several human tumor cell lines, including the breast adenocarcinoma MCF7, HeLa, epithelial carcinoma, prostate adenocarcinoma PC3, and human melanoma A375. "

Related Drugs and Biologics

1.	Diterpenes
2.	salvipisone
3.	Abietanes
4.	ferruginol
5.	quinone (benzoquinone)