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11- deoxy- 11alpha- (2- hydroxyethylthio)- prostaglandin E2 methyl ester
Also Known As:
11-deoxy-11alpha-(2-hydroxyethylthio)-PGE2 methyl ester; DHET-PGE2; Prosta-5,13-dien-1-oic acid, 15-hydroxy-11-((2-hydroxyethyl)thio)-9-oxo-, methyl ester, (5Z,11alpha,13E,15S)-
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Lipids: 114793
Fatty Acids: 27405
Unsaturated Fatty Acids: 8236
Eicosanoids: 3262
Prostaglandins: 17100
Prostaglandins E: 2673
Dinoprostone: 10047
11-deoxy-11alpha-(2-hydroxyethylthio)-prostaglandin E2 methyl ester: 1
Biological Factors: 2472
Inflammation Mediators: 1113
Autacoids: 276
Eicosanoids: 3262
Prostaglandins: 17100
Prostaglandins E: 2673
Dinoprostone: 10047
11-deoxy-11alpha-(2-hydroxyethylthio)-prostaglandin E2 methyl ester: 1
Related Diseases
1.
Bronchial Spasm
03/01/1981 - "
A C-11 substituted PGE2 analog, DHET-PGE2 [alpha-11-deoxy-11 alpha-(2-hydroxyethylthio)-PGE2 methyl ester], was demonstrated to exert potent bronchodilator activity in three in vivo models of augmented airway resistance: (1) acute bronchospasms, induced by 5-hydroxytryptamine, histamine and acetylcholine in the anesthetized guinea pig, (2) acute bronchospasm, induced by pilocarpine, in the anesthetized dog, and (3) chronic bronchospasm, induced by SO2 exposure, in the unanesthetized dog.
"
Related Drugs and Biologics
1.
Dinoprostone (PGE2)
2.
Serotonin (5 Hydroxytryptamine)
3.
Pilocarpine (Ocusert)
4.
Histamine (Histamine Dihydrochloride)
5.
Esters
6.
Bronchodilator Agents (Bronchodilators)
7.
Acetylcholine (Acetylcholine Chloride)