Autacoids

A chemically diverse group of substances produced by various tissues in the body that cause slow contraction of smooth muscle; they have other intense but varied pharmacologic activities.

Also Known As:

Networked: 127 relevant articles (1 outcomes, 8 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Serhan, Charles N: 9 articles (10/2014 - 04/2003)
2.	Clària, Joan: 5 articles (01/2016 - 06/2009)
3.	Titos, Esther: 4 articles (01/2016 - 06/2009)
4.	González-Périz, Ana: 3 articles (01/2012 - 06/2009)
5.	Greene, Emily R: 3 articles (12/2011 - 12/2010)
6.	Panigrahy, Dipak: 3 articles (12/2011 - 12/2010)
7.	Gronert, Karsten: 3 articles (06/2009 - 04/2003)
8.	Rius, Bibiana: 2 articles (01/2016 - 01/2012)
9.	López-Vicario, Cristina: 2 articles (01/2016 - 01/2012)
10.	García-Alonso, Verónica: 2 articles (01/2016 - 01/2012)

Related Diseases

1.	Malaria 08/01/2004 - "The study reveals that the production of autacoids in established infection renders autacoid inhibitors and an antagonist ineffective for radical cure in malarial mice; however, selective inhibition of local hormones implicated in the pathological manifestations of malaria infection by autacoid inhibitors and an antagonist may be a possible pathway to reduce the severity of infection and the associated tissue damage and to enhance the efficacy of available anti-malarials."
2.	Infection 08/01/2004 - "The study reveals that the production of autacoids in established infection renders autacoid inhibitors and an antagonist ineffective for radical cure in malarial mice; however, selective inhibition of local hormones implicated in the pathological manifestations of malaria infection by autacoid inhibitors and an antagonist may be a possible pathway to reduce the severity of infection and the associated tissue damage and to enhance the efficacy of available anti-malarials."
3.	Inflammation 08/21/2012 - "Studies over the past decade have elucidated that omega-3 PUFAs are enzymatically converted into bioactive autacoids that have inflammation-resolving properties. " 07/01/2007 - "The data obtained in this study support a scenario in which an increase in AGP concentration in pathological conditions suppresses inflammation reactions induced by autacoids and neutrophils activities and that AGP plays an important role in the maintenance in the body." 10/15/2014 - "Specialized proresolving lipid mediators (SPMs) are endogenous autacoids that actively promote resolution of inflammation. " 01/07/2014 - "Specialized proresolving lipid mediators (SPMs)-resolvins, protectins, and maresins-are novel autacoids that resolve inflammation, protect organs, and stimulate tissue regeneration. " 12/01/2013 - "Here, we review the current knowledge on the role of these endogenous autacoids in the resolution of adipose tissue inflammation with special emphasis on their functional actions on macrophages. "
4.	Myocardial Ischemia (Ischemic Heart Diseases) 01/01/2001 - "New aspects on Ca2+ antagonism during myocardial ischemia surprisingly related to endothelial autacoids." 04/01/1990 - "In this study, we examined the potential relation between production of reactive oxygen species and cyclooxygenase-derived autacoids by studying the effects of superoxide dismutase (SOD) and catalase (CAT) on the rise in thromboxane formation observed with myocardial ischemia and reperfusion. "
5.	Pulmonary Fibrosis (Hamman Rich Syndrome) 10/01/1987 - "The purpose of this study was to determine if asbestos-induced pulmonary fibrosis in the rat can affect the levels of autacoids and peptides in freshly isolated lung cells. "

Related Drugs and Biologics

1.	Hormones
2.	Antimalarials (Antimalarial Agents)
3.	Histamine (Histamine Dihydrochloride)
4.	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)
5.	Peptides
6.	Reactive Oxygen Species (Oxygen Radicals)
7.	Endocannabinoids (Endocannabinoid)
8.	Angiogenic Proteins
9.	Loratadine (Alavert)
10.	Terfenadine (Seldane)

Related Therapies and Procedures

1.	Ischemic Postconditioning
2.	Subcutaneous Injections