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purine phosphoribosyltransferase

specific purine phosphoribosyltransferases are EC 2.4.2.7 and 2.4.2.8.

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Glycosyltransferases: 784
      - Pentosyltransferases
        purine phosphoribosyltransferase: 7

Experts

1.	Basso, Luiz A: 1 article (08/2009)
2.	Biazus, Gisele: 1 article (08/2009)
3.	Palma, Mario S: 1 article (08/2009)
4.	Santos, Diógenes S: 1 article (08/2009)
5.	Schneider, Cristopher Z: 1 article (08/2009)

Related Diseases

1.	Lesch-Nyhan Syndrome (Choreoathetosis Self Mutilation Hyperuricemia Syndrome) 01/01/1981 - "[Erythrocyte purine phosphoribosyltransferase activity in girls with the Lesch-Nyhan syndrome]." 07/01/1984 - "[Effect of a purine-free diet on the purine phosphoribosyltransferase activity of erythrocytes in patients with Lesch-Nyhan syndrome]."
2.	Lewis Lung Carcinoma 06/01/1984 - "The purine phosphoribosyltransferase activities were also higher than that of amidophosphoribosyltransferase in Lewis lung carcinoma (8.2- to 32-fold), human renal cell carcinoma (3.5- to 22-fold), and hepatocellular carcinoma (3.4- to 30-fold). "
3.	Parasitic Diseases (Parasitic Disease) 08/01/2009 - "Enzymes of the purine phosphoribosyltransferase (PRTase) family are components of purine salvage pathway and have been proposed as drug targets for the development of chemotherapeutic agents against infective and parasitic diseases. "
4.	Malaria 08/01/1988 - "The properties of a purine phosphoribosyltransferase from late trophozoites of the human malaria parasite, Plasmodium falciparum, are described. " 08/01/1988 - "Properties and substrate specificity of a purine phosphoribosyltransferase from the human malaria parasite, Plasmodium falciparum."
5.	Hepatocellular Carcinoma (Hepatoma) 06/01/1984 - "The purine phosphoribosyltransferase activities were also higher than that of amidophosphoribosyltransferase in Lewis lung carcinoma (8.2- to 32-fold), human renal cell carcinoma (3.5- to 22-fold), and hepatocellular carcinoma (3.4- to 30-fold). "

Related Drugs and Biologics

1.	purine
2.	Enzymes
3.	Amidophosphoribosyltransferase