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AVR-25

oligosaccharide compound, chitohexaose analog

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Macromolecular Substances: 97
- Polymers: 13051
  - Biopolymers: 773
    - Chitin: 898
      - AVR-25: 3
Carbohydrates: 22023
- Polysaccharides: 15383
  - Chitin: 898
    - AVR-25: 3

Experts

1.	Acharya, Suchismita: 3 articles (03/2021 - 01/2019)
2.	Agarwal, Beamon: 3 articles (03/2021 - 01/2019)
3.	Bhandari, Vineet: 3 articles (03/2021 - 01/2019)
4.	Das, Pragnya: 3 articles (03/2021 - 01/2019)
5.	Shah, Dilip: 2 articles (03/2021 - 09/2020)
6.	Christensen, Dale J: 1 article (03/2021)
7.	Robertson, Stella M: 1 article (03/2021)
8.	Prahaladan, Varsha: 1 article (09/2020)
9.	Ali, Syed M: 1 article (01/2019)
10.	Behera, Sumita: 1 article (01/2019)

Related Diseases

1.	Lung Injury 03/04/2021 - "Further, AVR-25 and AVR-48 mediated diminished lung inflammation was associated with reduced expression of lung adhesion molecules with improvement in pulmonary endothelial barrier function, pulmonary edema, and lung injury. "
2.	Pulmonary Edema 03/04/2021 - "Further, AVR-25 and AVR-48 mediated diminished lung inflammation was associated with reduced expression of lung adhesion molecules with improvement in pulmonary endothelial barrier function, pulmonary edema, and lung injury. "
3.	Pneumonia (Pneumonitis) 03/04/2021 - "Further, AVR-25 and AVR-48 mediated diminished lung inflammation was associated with reduced expression of lung adhesion molecules with improvement in pulmonary endothelial barrier function, pulmonary edema, and lung injury. "
4.	Inflammation (Inflammations) 03/04/2021 - "Both chitin derivatives, AVR-25 and AVR-48, showed decreased neutrophil recruitment and reduced inflammation in the lungs of ALI mice. " 01/01/2019 - "Together, these findings demonstrate the therapeutic ability of AVR-25 to mitigate the storm of inflammation and minimize tissue injury with high potential for adjunctive therapy in intra-abdominal sepsis."
5.	Coinfection 01/01/2019 - "Following the cecal ligation and puncture (CLP) procedure, intravenous dosing of AVR-25 (10 mg/kg, 6-12 h post-CLP) alone and in combination with antibiotic imipenem protected both young adult (10-12 week old) and aged (16-18 month old) mice against polymicrobial infection, organ dysfunction, and death. "

Related Drugs and Biologics

1.	Chitin
2.	Imipenem
3.	Anti-Bacterial Agents (Antibiotics)

Related Therapies and Procedures

1.	Therapeutics
2.	Punctures
3.	Ligation