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3,4-difluorobenzylidenecurcumin

has antineoplastic activity; structure in first source

Also Known As:

3,4-difluorobenzylidene curcumin

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Banerjee, Sanjeev: 3 articles (12/2015 - 08/2015)
2.	Iyer, Arun K: 3 articles (12/2015 - 08/2015)
3.	Kesharwani, Prashant: 3 articles (12/2015 - 08/2015)
4.	Padhye, Subhash: 3 articles (12/2015 - 08/2015)
5.	Sarkar, Fazlul H: 3 articles (12/2015 - 08/2015)
6.	Han, Jiyou: 1 article (01/2021)
7.	Kim, Ji Hyeon: 1 article (01/2021)
8.	Kim, Jong Seung: 1 article (01/2021)
9.	Lee, Junhyoung: 1 article (01/2021)
10.	Sessler, Jonathan L: 1 article (01/2021)

Related Diseases

1.	Pancreatic Neoplasms (Pancreatic Cancer) 09/14/2015 - "Hyaluronic Acid Engineered Nanomicelles Loaded with 3,4-Difluorobenzylidene Curcumin for Targeted Killing of CD44+ Stem-Like Pancreatic Cancer Cells." 08/01/2015 - "Parenterally administrable nano-micelles of 3,4-difluorobenzylidene curcumin for treating pancreatic cancer." 12/01/2015 - "Hyaluronic acid-conjugated polyamidoamine dendrimers for targeted delivery of 3,4-difluorobenzylidene curcumin to CD44 overexpressing pancreatic cancer cells."
2.	Hypoxia (Hypoxemia) 01/01/2021 - "Several design elements are incorporated into AzCDF, including the CAIX inhibitor acetazolamide (Az) to promote localization in MDA-MB-231 CSCs, a dimethylnitrothiophene subunit as a hypoxia trigger, and a 3,4-difluorobenzylidene curcumin (CDF) as a readily released therapeutic payload. "

Related Drugs and Biologics

1.	Hyaluronic Acid (Hyaluronan)
2.	Dendrimers (Dendrons)
3.	Micelles
4.	Acetazolamide (Diamox)
5.	Poly(amidoamine)