|1.||da Silva Júnior, Eufrânio N: 4 articles (08/2014 - 06/2012)|
|2.||Ferreira, Vitor F: 4 articles (01/2014 - 02/2010)|
|3.||de Melo, Isadora M M: 3 articles (08/2014 - 06/2012)|
|4.||Emadi, Ashkan: 3 articles (12/2011 - 01/2010)|
|5.||Vuica-Ross, Milena: 3 articles (12/2011 - 01/2010)|
|6.||Ross, Ashley E: 3 articles (12/2011 - 01/2010)|
|7.||Camara, Celso A: 2 articles (03/2014 - 06/2012)|
|8.||Diogo, Emilay B T: 2 articles (03/2014 - 06/2012)|
|9.||de Oliveira, Ronaldo N: 2 articles (03/2014 - 06/2012)|
|10.||Valença, Wagner O: 2 articles (03/2014 - 06/2012)|
03/01/2014 - "The bhnq(2-) ligand is a "non-cytotoxic" agent that was chosen as a probe for the reactivity studies due to its suitable chromophoric properties, at the same time that it resembles more cytotoxic naphthoquinones relevant for cancer therapy. "
09/01/2006 - "Anti-cancer activities of 1,4-naphthoquinones: a QSAR study."
11/10/2003 - "As a continuation of our studies using natural and synthetic products as cancer chemopreventive agents, we examined the standard redox potentials of some naphthoquinones in phosphate buffer at pH 7.2 by means of cyclic voltammetry. "
03/01/2014 - "α-Lapachone- and nor-α-lapachone-based 1,2,3-triazoles and arylamino-substituted naphthoquinones showed potent cytotoxicity against different cancer cell lines. "
03/01/2014 - "The cytotoxic potential of the tested naphthoquinones was also assayed on non-tumor cells such as human peripheral blood mononucluear cells (PBMC) and two murine fibroblast lines (L929 and V79 cells). "
|2.||Chagas Disease (American Trypanosomiasis)
06/01/2012 - "Five 2-hydroxy-3-substituted-aminomethyl naphthoquinones, nine 1,2,3-triazolic para-naphthoquinones, five nor-β-lapachone-based 1,2,3-triazoles, and several other naphthoquinonoid compounds were synthesized and evaluated against the infective bloodstream form of Trypanosoma cruzi, the etiological agent of Chagas disease, continuing our screening program for new trypanocidal compounds. "
01/01/2011 - "Natural and synthetic naphthoquinones active against Trypanosoma cruzi: an initial step towards new drugs for Chagas disease."
01/01/1987 - "This paper describes the testing of several naphthoquinones, some of which were active against blood trypomastigotes in vitro at 4 degrees C and might therefore warrant further study for preventing transmission of Chagas disease by blood transfusion."
01/03/2003 - "In this work, the activities of three new pyrazolylnaphthoquinones, heterocyclic naphthoquinones bearing 3-aminopyrazole rings, were evaluated on Trypanosoma cruzi, the etiological agent of Chagas' disease. "
10/01/1990 - "Knowing the need for new drugs against the etiologic agent of Chagas disease and considering the biological properties of naphthoquinones and isoxazoles, the effect of three isoxazolyl-naphthoquinones on the growth of Trypanosoma cruzi was studied. "
09/01/2002 - "Activity of natural and synthetic naphthoquinones against Toxoplasma gondii, in vitro and in murine models of infection."
12/01/2000 - "A series of monomeric and dimeric naphthoquinones with potential for treatment of Leishmania infections was identified in vitro using both a direct cytotoxicity assay against extracellular promastigotes of Leishmania donovani, L. "
09/18/2000 - "A series of monomeric and dimeric naphthoquinones with potential for treatment of Leishmania infections was identified in vitro using both a direct cytotoxicity assay against extracellular promastigotes of Leishmania donovani, Leishmania infanturn, Leishmania enriettii, and Leishmania major and a test against intracellular amastigote L. "
04/01/1985 - "Efficacy of naphthoquinones and imidocarb dipropionate on Theileria sergenti infections in splenectomized calves."
03/01/1981 - "A variety of naphthoquinones have veen prepared and evaluated in vitro against the causative agent of the cattle disease East Coast Fever-Theileria parva infection. "
12/01/2012 - "The efficacy of three amino-terpenyl naphthoquinones and the alkaloid liriodenine were examined against tachyzoites and tissues cysts of the RH and EGS strains, respectively. "
03/01/2007 - "Vegetative dinoflagellate cysts exposed to 2.0 mg/L of the naphthoquinones juglone, plumbagin, menadione and naphthazarin showed varying degrees of chloroplast destruction, with menadione demonstrating the most potency. "
|1.||Blood Transfusion (Blood Transfusions)
|2.||Traditional Medicine (Folk Remedies)
|3.||Drug Therapy (Chemotherapy)