Aromatic Polycyclic Hydrocarbons (Polycyclic Aromatic Hydrocarbons)

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617 relevant articles (7 outcomes, 76 trials/studies) found for this Bio-Agent

Description: A major group of unsaturated cyclic hydrocarbons containing two or more rings. The vast number of compounds of this important group, derived chiefly from petroleum and coal tar, are rather highly reactive and chemically versatile. The name is due to the strong and not unpleasant odor characteristic of most substances of this nature. (From Hawley's Condensed Chemical Dictionary, 12th ed, p96)

Also Known As:

Polycyclic Aromatic Hydrocarbons; Polynuclear Aromatic Hydrocarbons; Polycyclic Hydrocarbons, Aromatic; Aromatic Hydrocarbons, Polycyclic; Aromatic Hydrocarbons, Polynuclear; Hydrocarbons, Aromatic Polycyclic; Hydrocarbons, Polycyclic Aromatic; Hydrocarbons, Polynuclear Aromatic

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Kauppinen, Timo: 4 articles (08/2007 - 09/2003)
2.	Boffetta, Paolo: 4 articles (08/2007 - 09/2003)
3.	Kromhout, Hans: 3 articles (08/2007 - 09/2003)
4.	Shaham, Judith: 3 articles (08/2007 - 09/2003)
5.	Johansen, Christoffer: 3 articles (08/2007 - 09/2003)
6.	Burstyn, Igor: 3 articles (08/2007 - 09/2003)
7.	Ferro, Gilles: 3 articles (08/2007 - 09/2003)
8.	Farmer, Peter B: 3 articles (07/2007 - 11/2003)
9.	Kalina, Ivan: 3 articles (07/2007 - 11/2003)
10.	Yu, Hongtao: 3 articles (06/2007 - 11/2002)

Related Diseases

1.	Neoplasms (Cancer) 02/01/2005 - "Previous studies of lung tumors from both non-smoking women and smoking men in this region showed high frequencies of mutations, consisting mostly of G-->T transversions in the p53 tumor suppressor gene and K-ras oncogene, suggesting that these mutations were caused primarily by polycyclic aromatic hydrocarbons. " 01/01/2000 - "The long-range goal of the present study is the development of a general approach for in vivo dosimetry of reactive metabolites of polycyclic aromatic hydrocarbons (PAHs), to be used as a tool in cancer risk assessment. " 01/01/1984 - "Animal studies have linked aryl hydrocarbon hydroxylase (AHH) with cancer induction by polycyclic aromatic hydrocarbons (PAH), but the relationship between the activation of PAH by AHH and cancer induction in man is unclear. " 01/01/2009 - "Polycyclic aromatic hydrocarbons (PAH) are established cancer initiators that can be found in our food and environment. " 02/01/2008 - "Estrogenic status is thought to influence the cancer risk in women and has been reported to affect toxicity of carcinogenic polycyclic aromatic hydrocarbons (PAHs) in animals. " Order ALL the reference details at left...
2.	Stomach Neoplasms (Stomach Cancer) 01/01/1985 - "Frequent consumption of cured, pickled, or smoked foods, possibly because they may contain nitrosamines or polycyclic aromatic hydrocarbons, appears to increase the risk of esophageal or stomach cancer, however, the specific causative agents in these foods are not clearly identified. " 06/01/1983 - "In contrast, frequent consumption of salt-cured, salt-pickled, or smoked foods, possibly because they may contain nitrosamines or polycyclic aromatic hydrocarbons, appears to increase the risk of esophageal or stomach cancer. " Order ALL the reference details at left...
3.	DNA Damage 07/01/2008 - "Taken together, these results suggest that PXR plays an important role in protection against DNA damage by polycyclic aromatic hydrocarbons (PAHs) such as BaP, and that these protective effects may be through a coordinated regulation of genes involved in xenobiotic metabolism." 10/01/2009 - "Occupational exposure to polycyclic aromatic hydrocarbons and DNA damage by industry: a nationwide study in Germany." 07/01/2007 - "The aim of this study was to investigate a possible influence of occupational exposure to carcinogenic environmental polycyclic aromatic hydrocarbons (c-PAHs) on cellular susceptibility to the induction of the DNA damage. " 07/01/2007 - "Effects of polycyclic aromatic hydrocarbons (PAHs) in environmental pollution on exogenous and oxidative DNA damage (EXPAH project): description of the population under study." 03/01/2005 - "This study suggests that the fetus may be 10-fold more susceptible to DNA damage than the mother and that in utero exposure to polycyclic aromatic hydrocarbons may disproportionately increase carcinogenic risk. " Order ALL the reference details at left...
4.	Hemolysis 01/22/1981 - "The observed inhibition of two membrane functions by the polycyclic aromatic hydrocarbons does not correlate simply with their theoretical octanol/water partition coefficients, water solubilities, or ability to confer membrane stabilization against osmotic hemolysis. " 02/01/1976 - "The polycyclic aromatic hydrocarbons, 3-methylcholanthrene and benz[a]anthracene, confer little protection against hemolysis and simultaneous incubation of nonprotective 3-methylcholanthrene and protective 3'-methyldimethylaminoazobenzene slightly alters the stabilization afforded by the latter. " Order ALL the reference details at left...
5.	Syndrome 10/01/1992 - "Genetic deficiencies in bilirubin UDP-glucuronosyltransferase (GT) occur in >5% of the population (Gilbert's disease, Crigler-Najjar syndromes), and this could predispose such people to the toxic effects of polycyclic aromatic hydrocarbons and other environmental chemicals that are eliminated substantially by glucuronidation. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Nitrosamines
2.	Epoxy Compounds (Epoxides)
3.	Methylcholanthrene
4.	benz(a)anthracene (benzanthracene)
5.	Protein Isoforms (Isoforms)
6.	Sterols
7.	bilirubin glucuronoside glucuronosyltransferase
8.	lathosterol
9.	Carcinogens
10.	Benzo(a)pyrene

Related Therapies and Procedures

1.	Electrodes (Electrode)
2.	Nuclear Power Plants

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