diospyrin

09/01/2008 - "Moreover, diospyrin and all its derivatives were found to show significantly greater (approximately 17- to 1441-fold) cytotoxicity against the tumor cells as compared to normal human lymphocytes. "
01/11/2020 - "Diospyrin is a bisnaphthoquinonoid medicinal compound derived from Diospyros lotus, with known anti-cancer, anti-tubercular, and anti-leishmanial activities against Leishmania donovani. "
09/01/2010 - "Our review is focused on the pro-apoptotic/anti-cancer activities of diospyrin, its derivatives/analogues and the different mechanisms potentially involved in the bioactivity of these compounds. "
09/01/2010 - "Diospyrin, a plant based bisnaphthoquinonoid, has been used as a lead molecule in an effort to develop anti-cancer drugs. "
09/01/2010 - "Anti-cancer activities of diospyrin, its derivatives and analogues."

12/01/2023 - "Neuroprotective evaluation of diospyrin against drug-induced Alzheimer's disease."
12/01/2023 - "A current investigation was performed to assess the neuroprotective effect of Diospyrin, a novel therapeutic agent, for the curing of Alzheimer's disease. "

09/01/2008 - "malignant skin melanoma and epidermoid laryngeal carcinoma (IC50=0.06 and 0.92 microM, respectively) in comparison to the natural precursor, diospyrin (IC50=0.82 and 3.58 microM, respectively). "
08/01/1984 - "Biological activity of diospyrin towards Ehrlich ascites carcinoma in Swiss A mice."
10/07/2007 - "Novel glycoconjugates of diospyrin, a quinonoid plant product: synthesis and evaluation of cytotoxicity against human malignant melanoma (A375) and laryngeal carcinoma (Hep2)."
01/01/1987 - "Diospyrin, a bis-naphthoquinone derivative, isolated from a plant, known for its antitumour properties against Ehrlich ascites carcinoma in Swiss A mice, exhibits antiprotozoal activity towards L. "
06/01/2007 - "Derivatisation of diospyrin, a bisnaphthoquinonoid isolated from Diospyros montana Roxb., led to the modification of its inhibitory activity, in vitro, towards a murine tumour model, Ehrlich ascites carcinoma (EAC), and two human cancer cell lines, viz., malignant skin melanoma (A375) and epidermoid laryngeal carcinoma (Hep2). "

06/17/2005 - "With the goal to reduce the toxicity towards normal cells and enhance the efficacy to tumour cells, diospyrin was encapsulated in liposomal vesicle and its antitumour potential was observed on the growth of Ehrlich ascites tumour in Swiss mice. "
08/01/1984 - "Biological activity of diospyrin towards Ehrlich ascites carcinoma in Swiss A mice."
01/01/1987 - "Diospyrin, a bis-naphthoquinone derivative, isolated from a plant, known for its antitumour properties against Ehrlich ascites carcinoma in Swiss A mice, exhibits antiprotozoal activity towards L. "
06/01/2007 - "Derivatisation of diospyrin, a bisnaphthoquinonoid isolated from Diospyros montana Roxb., led to the modification of its inhibitory activity, in vitro, towards a murine tumour model, Ehrlich ascites carcinoma (EAC), and two human cancer cell lines, viz., malignant skin melanoma (A375) and epidermoid laryngeal carcinoma (Hep2). "

09/01/2008 - "malignant skin melanoma and epidermoid laryngeal carcinoma (IC50=0.06 and 0.92 microM, respectively) in comparison to the natural precursor, diospyrin (IC50=0.82 and 3.58 microM, respectively). "
10/07/2007 - "Novel glycoconjugates of diospyrin, a quinonoid plant product: synthesis and evaluation of cytotoxicity against human malignant melanoma (A375) and laryngeal carcinoma (Hep2)."
06/01/2007 - "Derivatisation of diospyrin, a bisnaphthoquinonoid isolated from Diospyros montana Roxb., led to the modification of its inhibitory activity, in vitro, towards a murine tumour model, Ehrlich ascites carcinoma (EAC), and two human cancer cell lines, viz., malignant skin melanoma (A375) and epidermoid laryngeal carcinoma (Hep2). "