cypripedin

sensitizing agent for contact dermatitis from Lady Slipper (Cypripedium calceolus); structure

Also Known As:

2,8-dimethoxy-7-hydroxy-1,4-phenanthraquinone; 1,4-Phenanthrenedione, 7-hydroxy-2,8-dimethoxy-

Networked: 4 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Naphthoquinones: 418
        cypripedin: 4
- Quinones: 434
  - Naphthoquinones: 418
    - cypripedin: 4
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Naphthoquinones: 418
      - cypripedin: 4

Experts

1.	Sritularak, Boonchoo: 4 articles (01/2020 - 01/2018)
2.	Pongrakhananon, Varisa: 3 articles (03/2018 - 01/2018)
3.	Treesuwan, Surassawadee: 3 articles (03/2018 - 01/2018)
4.	Wattanathamsan, Onsurang: 2 articles (03/2018 - 01/2018)
5.	Böttcher, Chotima: 1 article (01/2020)
6.	Dehlinger, Adeline: 1 article (01/2020)
7.	Khoonrit, Pichayatri: 1 article (01/2020)
8.	Likhitwitayawuid, Kittisak: 1 article (01/2020)
9.	Mekboonsonglarp, Wanwimon: 1 article (01/2020)
10.	Mirdogan, Alp: 1 article (01/2020)

Related Diseases

1.	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/01/2018 - "In this study, we found that cypripedin attenuated typical mesenchymal phenotypes, including migratory behaviour, of non-small cell lung cancer H460 cells, with a significant reduction of actin stress fibres and focal adhesion and with weakened anchorage-independent growth. " 01/01/2018 - "Cypripedin diminishes an epithelial-to-mesenchymal transition in non-small cell lung cancer cells through suppression of Akt/GSK-3β signalling." 03/01/2018 - "Cypripedin, a phenanthrenequinone from Dendrobium densiflorum, sensitizes non-small cell lung cancer H460 cells to cisplatin-mediated apoptosis." 01/01/2018 - "Correction to: Cypripedin, a phenanthrenequinone from Dendrobium densiflorum, sensitizes non-small cell lung cancer H460 cells to cisplatin-mediated apoptosis."
2.	Neoplasm Metastasis (Metastasis) 01/01/2018 - "The observation in another lung cancer H23 cell line also supported this finding, indicating that cypripedin exhibits a promising pharmacological action on lung cancer metastasis that could provide scientific evidence for the further development of this compound." 01/01/2020 - "Dendrobium bibenzyls and phenanthrenes such as chrysotoxine, cypripedin, gigantol and moscatilin have been reported to show promising inhibitory effects on lung cancer growth and metastasis in ex vivo human cell line models, suggesting their potential for clinical application in patients with lung cancer. "
3.	Lung Neoplasms (Lung Cancer) 01/01/2018 - "The observation in another lung cancer H23 cell line also supported this finding, indicating that cypripedin exhibits a promising pharmacological action on lung cancer metastasis that could provide scientific evidence for the further development of this compound." 01/01/2020 - "Dendrobium bibenzyls and phenanthrenes such as chrysotoxine, cypripedin, gigantol and moscatilin have been reported to show promising inhibitory effects on lung cancer growth and metastasis in ex vivo human cell line models, suggesting their potential for clinical application in patients with lung cancer. "

Related Drugs and Biologics

1.	Cisplatin (Platino)
2.	Phenanthrenes
3.	Bibenzyls
4.	chrysotoxine
5.	gigantol
6.	dendrophenol