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2-amino-3-chloro-1,4-naphthoquinone

has antineoplastic activity; structure in first source

Also Known As:

2-ACl-NQ; quinoclamine

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Naphthoquinones: 418
        2-amino-3-chloro-1,4-naphthoquinone: 2
- Quinones: 434
  - Naphthoquinones: 418
    - 2-amino-3-chloro-1,4-naphthoquinone: 2
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Naphthoquinones: 418
      - 2-amino-3-chloro-1,4-naphthoquinone: 2

Experts

1.	Axelstad, Marta: 1 article (01/2017)
2.	Boberg, Julie: 1 article (01/2017)
3.	Christiansen, Sofie: 1 article (01/2017)
4.	Hass, Ulla: 1 article (01/2017)
5.	Scholze, Martin: 1 article (01/2017)
6.	Chen, J-C: 1 article (07/2009)
7.	Cheng, W-Y: 1 article (07/2009)
8.	Chiang, S-Y: 1 article (07/2009)
9.	Ho, T-Y: 1 article (07/2009)
10.	Hsiang, C-Y: 1 article (07/2009)

Related Diseases

1.	Neoplasms (Cancer) 07/01/2009 - "Quinoclamine affected the expression levels of genes involved in cell cycle or apoptosis, suggesting that quinoclamine exhibited anti-cancer potential. " 07/01/2009 - "Our findings suggest that quinoclamine is a novel NF-kappaB inhibitor with anti-cancer potential." 07/01/2009 - "Here, we have evaluated the anti-cancer potential of a novel NF-kappaB inhibitor, quinoclamine (2-amino-3-chloro-1,4-naphthoquinone). "
2.	Breast Neoplasms (Breast Cancer) 07/01/2009 - "Quinoclamine also inhibited induced NF-kappaB activities in lung and breast cancer cell lines. "
3.	Birth Weight (Birth Weights) 01/01/2017 - "We hypothesized that a mixture of six pesticides (cyromazine, MCPB, pirimicarb, quinoclamine, thiram, and ziram) would decrease birth weight, and that these mixture effects could be predicted by the Dose Addition model. "

Related Drugs and Biologics

1.	NF-kappa B (NF-kB)
2.	Ziram (Zinc Dimethyldithiocarbamate)
3.	Thiram
4.	cyromazine
5.	pirimicarb
6.	2-methyl-4-chlorophenoxy gamma-butyric acid (MCPB)