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artemisinin-naphthoquine combination

a fixed oral dose artemisinin-naphthoquine combination undergoing clinical trials for uncomplicated falciparum malaria in adults of Papua New Guinea; 3/2009
Also Known As:
ANQ combination; ARCO
Networked: 169 relevant articles (11 outcomes, 31 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Drescher, Wolf: 7 articles (06/2021 - 12/2009)
2. Lee, Mel S: 7 articles (06/2021 - 05/2015)
3. Cheng, Edward Y: 6 articles (06/2021 - 01/2019)
4. Cui, Quanjun: 6 articles (06/2021 - 01/2019)
5. Goodman, Stuart B: 6 articles (06/2021 - 01/2019)
6. Jones, Lynne C: 6 articles (06/2021 - 01/2019)
7. Mont, Michael A: 6 articles (06/2021 - 01/2019)
8. Sugano, Nobuhiko: 6 articles (06/2021 - 01/2019)
9. Yamamoto, Takuaki: 6 articles (06/2021 - 01/2019)
10. He, Wei: 5 articles (01/2022 - 07/2020)

Related Diseases

1. Pain (Aches)
01/01/2023 - "The primary efficacy endpoint was the composite treatment response at 24 months, comprising the clinical response (clinically important improvement in pain from baseline using the WOMAC VA3.1 pain subscale, defined as 10 mm on a 100-mm scale) and radiologic response (the absence of progression to fracture stage [≥ ARCO Stage III], as assessed by conventional radiography and MRI of the hips). "
01/01/2023 - "The study was discontinued because our data safety monitoring board recommended terminating the study for futility based on preselected futility stopping rules: conditional power below 0.20 and p = 0.01 to detect an effect size of 10 mm on the 100-mm WOMAC VA3.1 pain subscale (improvement in pain) and the absence of progression to fracture (≥ ARCO Stage III) observed on radiologic assessment, reflecting the unlikelihood that statistically beneficial results would be reached at 24 months after the treatment. "
02/02/2018 - "The results of the current study indicated that ESWT is an effective treatment method for nontraumatic ONFH, resulting in pain relief and function restoration, especially for patients with ARCO stage I-II ONFH."
04/01/2012 - "The current study evaluated the effectiveness of ESWT in reducing pain and in slowing down the progression of bone damage in 36 patients with unilateral AVNFH of stage Association Research Circulation Osseous (ARCO) I, II and III. At the beginning of the study, 10 hips were classified as stage I, 11 as stage II and 15 as stage III. Each treatment cycle included four sessions, with 2,400 impulses each administered at 0.50 mJ/mm(2), at 48-72 h intervals. "
09/27/2023 - "Thirty-six patients were grouped based on the Association Research Circulation Osseous (ARCO) classification, and 28 healthy volunteers without hip pain or any lesions shown in anteroposterior and frog-leg lateral pelvic radiographs served as the normal control group. "
2. Osteonecrosis (Kienbock's Disease)
3. Rheumatoid Arthritis
4. Necrosis
5. Allergic Rhinitis

Related Drugs and Biologics

1. Iloprost (Ventavis)
2. Tantalum
3. Chloroquine (Aralen)
4. Antirheumatic Agents (DMARD)
5. Niacinamide (Nicotinamide)
6. tongluo
7. carbogen
8. pyrimethamine drug combination fanasil (Fansidar)
9. Therapeutic Uses
10. Steroids

Related Therapies and Procedures

1. Therapeutics
2. Decompression
3. Osteotomy
4. Surgical Flaps
5. Radiotherapy