Abstract | AIMS: METHODS: This cross-sectional study included a total of 499 subjects aged 50 years or over. Multivariate regression analysis was conducted to clarify the association of different forms of obesity with adipose tissue insulin resistance (calculated as fasting insulin level×fasting free fatty acids level). Receiver operating characteristic cure analyses were used to assess the diagnostic value of each anthropometric indicator for adipose tissue insulin resistance. Attributable risk per cent and population attributable risk per cent were calculated to assess the contribution of obesity to adipose tissue insulin resistance. RESULTS: CONCLUSIONS: Maintaining WC in males and BMI in females to a normal range could be an important strategy to significantly reduce the occurrence of adipose tissue insulin resistance and the subsequent metabolic diseases.
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Authors | Jiajia Jiang, Xueli Cai, Yuesong Pan, Xiaoyan Du, Huiping Zhu, Xinghua Yang, Deqiang Zheng, Herbert Gaisano, Tiemin Wei, Yan He |
Journal | BMJ open diabetes research & care
(BMJ Open Diabetes Res Care)
Vol. 8
Issue 1
(04 2020)
ISSN: 2052-4897 [Electronic] England |
PMID | 32245824
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. |
Topics |
- Adipose Tissue
- Cross-Sectional Studies
- Diabetes Mellitus, Type 2
- Female
- Humans
- Insulin Resistance
- Male
- Obesity
(diagnosis, epidemiology)
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