Abstract | INTRODUCTION: METHODS: In this double-blind, randomized clinical trial, patients aged 18 to 55 years who were admitted to the emergency department (ED) with limb fracture were recruited. A total of 127 patients were included in the study, 51.1% (65) of whom were male and 48.9% (62) of whom were female. The patients were divided equally into two groups: Group I received 100 cm3 IV infusion of normal saline and 4 μg/kg of 50 μg/ml nebulized fentanyl; Group II received 0.4 mg/kg ketamine in 10 min and 5 cm3 nebulized normal saline. Pain was assessed using a visual analog scale just before treatment and 5, 10, 15, 30, and 60 min post-treatment. RESULTS: Before intervention, the pain scores of both groups showed no significant difference. However, log linear analysis in both groups showed a significantly decrement during the follow up (60 min) (p < 0.0001). Multiple comparison analysis showed that pain scores were significantly higher in the patients of Group I. Moreover, patients in Group I required additional treatment. CONCLUSION:
Ketamine can be used as an alternative non-invasive treatment to successfully relieve pain in patients with limb fractures.
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Authors | Mohammadreza Maleki Verki, Javad Mozafari, Fateme Tirandaz, Hassan Motamed, Afsane Khazaeli |
Journal | African journal of emergency medicine : Revue africaine de la medecine d'urgence
(Afr J Emerg Med)
Vol. 9
Issue 3
Pg. 119-122
(Sep 2019)
ISSN: 2211-4203 [Electronic] Netherlands |
PMID | 31528528
(Publication Type: Journal Article)
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