Bone Fractures (Bone Fracture)

10/01/2007 - "Despite an apparent impact of tamoxifen on bone mineral density, the few available studies of tamoxifen and bone fractures appear to suggest no protective effect but an increase in fracture incidence. "
08/01/1998 - "To evaluate the association between tamoxifen (TAM) treatment and rate of bone fractures in older, nursing home residents. "
08/01/1998 - "Effect of tamoxifen on bone fractures in older nursing home residents."
12/01/2001 - "The Breast Cancer Prevention Trial (BCPT, P-1) demonstrated that tamoxifen can reduce the incidence of both invasive and noninvasive breast cancer as well as of bone fractures in women at increased risk. "
03/01/1994 - "The Breast Cancer Prevention Trial (BCPT), under the auspices of the National Surgical Adjuvant Breast and Bowel Project (NSABBP), will evaluate the effect of tamoxifen in reducing the incidence of invasive breast cancer, breast cancer mortality, cardiovascular mortality, and bone fractures. "

05/01/2009 - "Although further studies relating to the mechanism for possible impaired bone strength in these patients will be needed, bisphosphonates may be beneficial treatment for prevention of bone fractures in patients with severe risk for fractures, such as post-menopausal women."
01/01/2013 - "Although antiresorptive bisphosphonates have been widely used to treat pediatric OI, controlled trials show improved vertebral parameters but equivocal effects on long-bone fracture rates. "
02/01/2015 - "Anti-resorptive bisphosphonates are frequently used to treat pediatric OI and controlled clinical trials have shown that bisphosphonate therapy improves vertebral outcomes but has little benefit on long bone fracture rate. "
05/01/2015 - "Bisphosphonates are widely used to prevent bone fractures. "
05/01/2014 - "Because bisphosphonates have been proven to prevent bone fracture in GIO, we tried to detect the therapeutic effects of bisphosphonates in GIO by MDCT. "

04/01/2009 - "The findings, assessed on the basis of biochemical, bone mineral density, biomechanical, and histopathological parameters, showed that ICA has a definite antiosteoporotic effect, similar to estrogen, especially effective for prevention bone fracture induced by estrogen deficiency."
01/01/2013 - "Estrogen has an important role in osteogenesis and prevention of bone fractures. "
05/01/2009 - "There is the evidence that estrogens prevent bone fractures in not only osteoporotic women but also healthy women. "
05/01/1953 - "[Diet, estrogens and bone fractures]."
09/01/1995 - "Although the definitive answer is not yet available, recent epidemiologic data suggest no reduction in protection against CVD and bone fracture with the addition of progestin, which is referred to as hormone replacement therapy, as opposed to using estrogen alone. "

05/01/2009 - "Notably, the available evidence for raloxifene suggests that the efficacy of raloxifene in preventing bone fractures has not only to do with bone mineral density but also to do with bone quality."
10/01/2008 - "Notably, the available evidence for raloxifene suggests that the efficacy of raloxifene in preventing bone fractures has not only to do with bone mineral density but also to do with bone quality."
05/01/2009 - "Thus, this review has drawn mainly on the results of the MORE study to explore the efficacy of raloxifene in inhibiting bone metabolism, increasing bone mineral density effects, and preventing bone fractures. "
10/01/2008 - "Thus, this review has drawn mainly on the results of the MORE study to explore the efficacy of raloxifene in inhibiting bone metabolism, increasing bone mineral density effects, and preventing bone fractures. "
04/01/1998 - "In older postmenopausal women with existing bone fractures, raloxifene 60 or 120 mg/day for 1 year produced modest increases in bone mineral density. "

02/01/2006 - "Tolerability is improved with aromatase inhibitors, the major concern with the use of aromatase inhibitors being the development of osteoporosis and bone fractures. "
09/01/2014 - "Aromatase inhibitors associated musculoskeletal disorders and bone fractures in postmenopausal breast cancer patients: a result from Chinese population."
09/01/2009 - "The introduction for breast cancer of a new category of drugs, aromatase inhibitors, seems to be linked to an increase in bone fractures. "
01/01/2014 - "Despite their effectiveness in reducing tumor recurrence, aromatase inhibitors have adverse effects on the cardiovascular system and increase osteoporosis and bone fractures. "
01/01/2009 - "Results from directly comparative trials indicating the efficacy, tolerability and bone fracture risk of exemestane relative to third-generation aromatase inhibitors and other agents in both early-stage and advanced disease, as well as the optimal sequence of endocrine therapies, are awaited with interest. "

06/01/2006 - "Before interpretation of S-NTX, we should estimate glomerular filtration rate by using Cockcroft-Gault formula, especially in elderly patients with low body mass index such as rheumatic patients, whose S-Cr-is in normal ranges Both markers are very useful for estimating the risk of bone fracture and for monitoring therapeutic effects of anti-resorptive agents such as bisphosphonate or selective estrogen receptor modulator."
01/01/2015 - "Not having a prior bone fracture, being older, using a SERM and having less osteoporotic risk factors were all linked to less DALY losses."
01/01/2006 - "On the basis of the findings that a selective estrogen receptor modulator, raloxifene, showed a protective effect of bone fracture far more potent than its BMD-increasing effect, the hypothesis that bone marker indicates fracture risk independent of BMD has been raised and established."
09/01/2005 - "Evidence indicates raloxifene (RLX), a selective estrogen receptor modulator, is effective for a protection of bone fracture without increasing of breast cancer and endometrial cancer. "
04/01/2005 - "Evidence indicates that estrogen and raloxifene hydrochloride, a selective estrogen receptor modulator, prevent bone loss and reduce the risk of bone fractures in postmenopausal women. "

01/31/2012 - "Oral alendronate treatment reduces the incidence of bone fracture and improves physical activity and life quality in OI children, and as a well-tolerated regimen, it is both safe and effective in clinical practice."
08/01/2014 - "Alendronate-induced atypical bone fracture: evidence that the drug inhibits osteogenesis."
01/01/2008 - "This osteoporotic patient had been prescribed alendronate for radial bone fracture. "
04/01/2007 - "Five years on, five years off: taking a break from Fosamax won't result in broken bones."
09/01/2004 - "Alendronate that produces reduction in urinary NTx and inhibition of decrease in BMD may have a clinical significance to reduce the risk of bone fracture in postmenopausal type 2 diabetic women."

04/01/2004 - "It is generally accepted that supplemental Ca and/or vitamin D is effective in reducing the incidence of bone fractures; this is supported by numerous randomised controlled trials and meta-analyses. "
03/01/2010 - "Clinical studies have suggested a possible association of low serum vitamin D levels in patients with bone fractures. "
10/01/2015 - "To assess the implication of vitamin D and its relationship to bone fracture and fracture force, we have examined vitamin D levels in patients requiring inpatient fracture management. "
05/01/2015 - "Professional football players deficient in vitamin D levels may be at greater risk of bone fractures."
05/01/2015 - "When controlling for number of professional years played, vitamin D levels were significantly lower in players with at least 1 bone fracture when compared with no fractures. "

12/01/2001 - "Bisphosphonate therapy, therefore, appears to be an effective, well-tolerated means of reducing the risk of bone fractures among patients treated with corticosteroids."
10/01/2009 - "We conducted a meta-analysis of published studies of patients with long-bone fractures who were randomly assigned to groups receiving corticosteroids or standard treatment for the prevention of FES (1966-2006). "
10/01/2009 - "Our objective was to determine the effect of corticosteroids in preventing FES in patients with long-bone fractures. "
03/01/2004 - "Prevention of posttraumatic hypoxaemia in isolated lower limb long bone fractures with a minimal prophylactic dose of corticosteroids."
02/01/1998 - "The author demonstrates on a group of 292 patients (207 women, 85 men) treated on account of various diseases with corticoids laboratory parameters and bone density and records of bone fractures. "

11/01/2011 - "To compare the efficacy of sublingual midazolam with oral morphine versus that of oral morphine with placebo in a paediatric population attending an emergency department (ED) with acute long-bone fractures. "
03/01/2007 - "We compare the efficacy of intranasal fentanyl versus intravenous morphine in a pediatric population presenting to an emergency department (ED) with acute long-bone fractures. "
04/01/2012 - "We compare the efficacy and safety of sublingual buprenorphine versus intravenous morphine sulfate in emergency department adults with acute bone fracture. "
11/01/2011 - "The analgesic performances of morphine and the combination of morphine with midazolam assessed by VAS were similar in children presenting at the ED with a long-bone fracture."
11/01/2011 - "A sample of children aged 5-16 years with clinically deformed closed long-bone fractures was randomized to groups receiving either oral morphine (0.5 mg/kg)/sublingual placebo or oral morphine (0.5 mg/kg)/sublingual midazolam (0.2 mg/kg). "

02/01/2012 - "The objective of the study was to describe analgesia utilization before and during the emergency department (ED) visit and assess factors associated with analgesia use in pediatric patients with isolated long-bone fractures. "
01/01/2015 - "We recommend FICNB for analgesia after surgery for femoral bone fracture and for patients with femoral bone fracture at the emergency department."
11/01/2013 - "Does age affect analgesia provision at discharge among children with long bone fractures requiring emergency care?"
04/01/2013 - "Race, ethnicity, and analgesia provision at discharge among children with long-bone fractures requiring emergency care."
12/01/2011 - "The authors sought to determine which quality measures of analgesia delivery are most influenced by emergency department (ED) crowding for pediatric patients with long-bone fractures. "

01/01/2002 - "Bone defect is the most common cause of non-union of forearm bone fractures resulting from missile injury and early slivered cancellous bone graft is effective in the treatment of non-union."
05/01/2015 - "This article examines the efficacy of current evidence-based clinical interventions in reducing the incidence of bone fractures among recipients of kidney transplant."
01/01/2006 - "Future trials in the elderly should focus on such endpoints as PTDM, post-transplant neoplasia, cardiovascular events and bone fracture events in order to identify the safest regimens that provide the optimal control of rejection while limiting the morbidity from these secondary events."
01/01/2016 - "Complications, although low in occurrence, included partial skin pedicle loss, nonunion between the clavicular graft and the remaining inferior border of the mandible, and clavicular bone fracture. "
05/01/2015 - "Rapid bone density loss that occurs during the first year after transplant along with pre-existing bone disorder, places these patients at risk of bone fractures at three times higher than the general population. "

01/01/1991 - "Plates and screws are effective for rigid internal fixation of bone fractures and osteotomies in the midface, orbit, and cranium. "
01/01/1990 - "The author has studied on wound healing of the jaw bone fractures in 5 Malaysian monkeys aging around 2 years and weighing about 3 Kg. For the experimental studies, fractures of the jaw bone in terms of oblique osteotomies from angle to sigmoid notch of the mandible of the Malaysian monkeys were made by using #700 fissure bur and reduced and fixed them in terms of interosseous wiring. "
04/01/2015 - "Transtrochanteric osteotomy and subtrochanteric osteotomy can effectively adjust leg length, correct femoral anteversion and avoid nerve injury, but transtrochanteric osteotomy may cause bone fracture and abductor injury. "
08/01/2014 - "Sclerostin monoclonal antibody enhanced bone fracture healing in an open osteotomy model in rats."
08/01/2014 - "In this review, the principles of bone fracture healing and differences between osteotomy and artificial fracture models as well as influences of fixation devices are summarized. "

06/01/2014 - "Achieving good results with intramedullary nailing of oblique long bone fractures at the metaphyseal-diaphyseal junction can be difficult. "
07/20/2010 - "To determine the therapeutic efficacy of augmentation plate fixation in nonunion of long-bone fracture after interlocking intramedullary nailing. "
01/01/2013 - "This study reports the complications observed in children with long bone fractures treated using Elastic Stable Intramedullary Nailing (ESIN). "
09/01/1992 - "[A new intramedullary nailing system for long bone fractures--biomechanical evaluation and animal study of a new intramedullary nail]."
12/01/2015 - "A residual postoperative fracture gap between major bone fragments following intramedullary nailing of long-bone fractures is recognised as one of the major risk factors for delayed union and non-union. "

06/20/2012 - "Does timing to operative debridement affect infectious complications in open long-bone fractures? "
06/20/2012 - "Schenker, MD, et al.: “Does timing to operative debridement affect infectious complications in open long-bone fractures? "
06/01/2007 - "Injured Coalition combatants received high-level damage control orthopaedic care and initial debridements, with external fixation as the single most common means of long-bone fracture stabilization. "
09/01/2015 - "Early operative priorities for musculoskeletal injuries focus on the principles of damage-control orthopaedics, with early and aggressive debridement of soft-tissue wounds, vascular shunting or grafting to restore limb perfusion, and long-bone fracture stabilization via external fixation. "
04/01/2011 - "Other than wound debridement, the most commonly performed procedure was fixation of long bone fractures, which constituted approximately one third of all surgical procedures. "