Abstract |
Parkinson disease (PD) is a complex neurologic disorder that involves motor and nonmotor brain functions. PD is the second most common neurodegenerative disease after Alzheimer disease. Motor symptoms include resting tremor, cogwheel rigidity, extreme slowness of movement, shuffling gait, and impaired balance. Swallowing and speaking difficulties also are common. Nonmotor symptoms include depression, hallucinations, and sleep disturbances that seriously affect quality of life. There is no cure for PD but management of motor and nonmotor symptoms can improve quality of life. Carbidopa-levodopa is an effective initial treatment for motor symptoms of rigidity and resting tremors. Treatments for nonmotor symptoms include antidepressants, antipsychotics, and drugs for dementia. (This is an off-label use of some antidepressants, antipsychotics, and drugs for dementia.) A multidisciplinary approach to optimizing care can include physical and occupational therapy, speech therapy, and psychological therapy.
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Authors | James E McKinley, Allen Perkins |
Journal | FP essentials
(FP Essent)
Vol. 477
Pg. 16-21
(Feb 2019)
ISSN: 2159-3000 [Print] United States |
PMID | 30747508
(Publication Type: Journal Article)
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Copyright | Written permission from the American Academy of Family Physicians is required for reproduction of this material in whole or in part in any form or medium. |
Topics |
- Dementia
(etiology)
- Hallucinations
(etiology)
- Humans
- Parkinson Disease
(complications, diagnosis, therapy)
- Quality of Life
- Sleep Wake Disorders
(etiology)
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