Abstract | BACKGROUND: METHODS: A cohort of 135 prepubertal Caucasian children (age range 4.4-9.7 years) was studied in a controlled cross-sectional study. Seventy-seven children had been exposed to maternal GDM, and 58 children born after a normal pregnancy served as controls. The outcomes were height, weight, BMI, blood pressure, and biochemical markers of glucose and lipid metabolism and inflammation. RESULTS: CONCLUSIONS: Higher hs-CRP as a marker of low-grade inflammation was detected in prepubertal children exposed to maternal GDM, but no differences were seen in height, weight, BMI, or markers of glucose and lipid metabolism compared to control children. This finding may reflect an ongoing process of metabolic changes in children born after a GDM pregnancy.
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Authors | Leena Antikainen, Jarmo Jääskeläinen, Henrikki Nordman, Raimo Voutilainen, Hanna Huopio |
Journal | Hormone research in paediatrics
(Horm Res Paediatr)
Vol. 90
Issue 2
Pg. 109-115
( 2018)
ISSN: 1663-2826 [Electronic] Switzerland |
PMID | 30110707
(Publication Type: Journal Article)
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Copyright | © 2018 S. Karger AG, Basel. |
Topics |
- Case-Control Studies
- Child
- Child, Preschool
- Cohort Studies
- Cross-Sectional Studies
- Diabetes, Gestational
- Female
- Humans
- Inflammation
(etiology, pathology)
- Male
- Pregnancy
- Prenatal Exposure Delayed Effects
(blood, immunology)
- Severity of Illness Index
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