[Effects of 16 week aerobic exercise on baPWV and ABI of middle-aged and elderly patients].

Abstract

OBJECTIVES:

To investigate the interventional effects of 16-week aerobic exercises on the elderly's arteriosclerosis and its mechanism.

METHODS:

Twenty-seven elderly people with the average age of 62. 70 ±3. 26 joined a 16-week square dance/taijiquan exercise program that conducted 60 minutes each time, six times per week. Arterial stiffness and its related indexes such as systolic pressure(SBP), diastolic pressure(DBP), left brachial-ankle pulse wave velocity (L-baPWV), right brachial-ankle pulse wave velocity(R-baPWV), left ankle brachial index (L-ABI), right ankle brachial index(R-ABI), serum triglyceride(TG), total cholesterol(TC), high density lipoprotein cholesterol(HDL-c), low density lipoprotein cholesterol(LDL-c), superoxide dismutase(SOD), malondialdehyde(MDA) and glutathione peroxidase (GSH-Px) were detected at 3 time points including before exercise program, by the end of exercise for 8 weeks and 16 weeks.

RESULTS:

① Compared with pre-exercise, the R-baPWV and R-ABI of the elderly people were decreased at the end of the 8th week, and the L-baPWV, RbaPWV, R-ABI and L-ABI were decreased significantly at the end of the 16th week. ②Compared with pre-exercise, SBP and DBP were declined markedly (P<0.01, P<0.05) at the end of the 8th week, SBP, DBP and pulse pressure were decreased significantly (P<0.01, P<0.05) at the end of the 16th week. ③Compared with pre-exercise, TC and LDL-c were declined markedly (P<0.01) at the end of the 8th and the 16th week, and there was no difference of the level of TG and LDL-c between pre-exercise and post-exercise. ④There was no evident difference of serum level of SOD, GSH-Px, MDA between pre-exercise and post-exercise at the end of the 8th week. Compared with pre-exercise, the level of serum SOD, GSH-Px was increased evidently while the content of serum MDA was decreased significantly (P<0.01).

CONCLUSIONS:

Sixteen-week aerobic exercises could reduce baPWV and ABI levels, regulate blood pressure, blood lipids and lipid peroxides levels of the elderly evidently, thus improve the controlling quality of atherosclerosis.

• Authors: Ning-Chuan Li, Xia-Lian Yin, Xiu-Xia Wei, Wei Lu, Shi-Wen Shen, Lang Xiao, Yu-Long Hu
• Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology (Zhongguo Ying Yong Sheng Li Xue Za Zhi) Vol. 34 Issue 2 Pg. 145-149 (Feb 08 2018) ISSN: 1000-6834 [Print] China
• PMID: 29926679 (Publication Type: Journal Article)

Chemical References

• Triglycerides
• Malondialdehyde
• Cholesterol
• Glutathione Peroxidase
• Superoxide Dismutase

Topics

• Aged
• Ankle
• Ankle Brachial Index
• Arteriosclerosis (therapy)
• Blood Pressure
• Cholesterol (blood)
• Exercise
• Glutathione Peroxidase (blood)
• Humans
• Malondialdehyde (blood)
• Middle Aged
• Pulse Wave Analysis
• Superoxide Dismutase (blood)
• Triglycerides (blood)