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Acquired acrodermatitis enteropathica after gastric bypass surgery responsive to IV supplementation.

Abstract
Nutritional deficiency is rare in developed countries, but can be acquired from decreased nutrient intake, reduced absorption, and increased gastrointestinal excretion. We report a patient with acquired acrodermatitis enteropathica (AE) who exhibited low plasma zinc levels and concurrent nutritional deficiencies (pyridoxine, selenium and fatty acids). Our patient had undergone Roux-en-Y gastric bypass 13 years prior to presentation. The rash, consistent with AE clinically and histologically, nearly resolved one week after starting IV zinc supplementation, total parenteral nutrition, and micronutrient supplements. This case highlights the importance of long-term post-operative follow-up for gastric bypass patients who are at high risk for micronutrient and macronutrient deficiencies and illustrates the potential for rapid improvement with IV supplementation.
AuthorsJasmine Rana, Molly Plovanich, Elizabeth B Wallace, Chao Yang, Alvaro Laga Canales, Arash Mostaghimi
JournalDermatology online journal (Dermatol Online J) Vol. 22 Issue 11 (Nov 15 2016) ISSN: 1087-2108 [Electronic] United States
PMID28329567 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Trace Elements
  • Zinc
Topics
  • Acrodermatitis (diagnosis, drug therapy, pathology)
  • Administration, Intravenous
  • Adult
  • Female
  • Gastric Bypass
  • Humans
  • Malnutrition (diagnosis, therapy)
  • Parenteral Nutrition, Total
  • Postoperative Complications (diagnosis, drug therapy, pathology)
  • Trace Elements (therapeutic use)
  • Zinc (deficiency, therapeutic use)

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