Abstract | OBJECTIVE: PATIENTS AND METHODS: RESULTS: No differences were found in biomarker positivity between IBD patients with and without arthropathies. Significantly more biomarker positivity (P<0.001) was observed in RA patients compared with IBD patients with arthropathies. Also, smoking turned out to be significantly associated with positivity for IgM-RF or IgA-RF. CONCLUSION: Our findings suggest that there is no apparent clinical value in the detection of RA biomarkers in serum of IBD patients to help identify arthropathies.
|
Authors | Sanne J H Van Erp, Marije K Verheul, E W Nivine Levarht, Johan J van der Reijden, Désirée van der Heijde, Floris A van Gaalen, Daniel W Hommes, Gary L Norman, Zakera Shums, Michael Mahler, Hein W Verspaget, Leendert A Trouw, Andrea E van der Meulen-de Jong |
Journal | European journal of gastroenterology & hepatology
(Eur J Gastroenterol Hepatol)
Vol. 29
Issue 3
Pg. 345-348
(Mar 2017)
ISSN: 1473-5687 [Electronic] England |
PMID | 27926664
(Publication Type: Comparative Study, Journal Article)
|
Chemical References |
- Autoantibodies
- Biomarkers
- Immunoglobulin A
- Immunoglobulin M
- Peptides, Cyclic
- cyclic citrullinated peptide
- Rheumatoid Factor
|
Topics |
- Adult
- Autoantibodies
(blood)
- Biomarkers
(blood)
- Case-Control Studies
- Colitis, Ulcerative
(blood, diagnosis, epidemiology, immunology)
- Crohn Disease
(blood, diagnosis, epidemiology, immunology)
- Female
- Humans
- Immunoglobulin A
(blood)
- Immunoglobulin M
(blood)
- Joint Diseases
(blood, diagnosis, epidemiology, immunology)
- Male
- Middle Aged
- Netherlands
(epidemiology)
- Peptides, Cyclic
(immunology)
- Predictive Value of Tests
- Rheumatoid Factor
(blood)
- Seroepidemiologic Studies
- Serologic Tests
- Smoking
(adverse effects, blood, immunology)
|