Abstract | OBJECTIVE: METHODS: In total, 430 consecutive patients who underwent coronary angiography procedure and had documented total occlusion in at least 1 major coronary artery were investigated retrospectively. Degree of CCC was classified according to Cohen-Rentrop method. Serum free triiodothyronine (FT3), free thyroxine (FT4) and thyroid-stimulating hormone (TSH) were assessed by the chemiluminescence immunoassay technique. RESULTS: In spite of diabetes mellitus (p=0.019), smoking (p<0.001), and TSH (p<0.001), FT3 (p<0.001), FT4 (p=0.015), and subclinical hypothyroidism ( SCH) (p<0.001) ratios were significantly different between groups. In regression analysis, SCH (p=0.024), DM (p=0.021), smoking (p<0.001), and heart failure (p=0.029) were independent predictors of poor CCC development in multivariate model 1. When regression analyses were performed based on multivariate model 2, TSH (p<0.001), FT3 (p<0.001), heart failure (p=0.022), smoking (p<0.001), and hyperlipidemia (HPL) (p=0.046) were independent predictors of poor CCC development. CONCLUSION: In addition to traditional risk factors, SCH, higher serum TSH, and lower FT3 levels were associated with development of poor CCC in patients with obstructive CA.
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Authors | Mehmet Ballı, Mustafa Çetin, Hakan Taşolar, Onur Kadir Uysal, Mahmut Yılmaz, Mine Durukan, Zafer Elbasan, Murat Çaylı |
Journal | Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir
(Turk Kardiyol Dern Ars)
Vol. 44
Issue 2
Pg. 130-6
(Mar 2016)
ISSN: 1308-4488 [Electronic] Turkey |
PMID | 27111311
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Collateral Circulation
(physiology)
- Coronary Artery Disease
(blood, complications, epidemiology)
- Humans
- Hypothyroidism
(blood, complications, epidemiology)
- Multivariate Analysis
- Retrospective Studies
- Thyroid Hormones
(blood)
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