Thyroid Diseases (Thyroid Disease)

01/01/2005 - "Surgery, radioactive iodine, and suppressive doses of Lthyroxine are commonly used in the treatment of benign nodular thyroid disease, with the best results achieved with surgery. "
04/01/2014 - "An easy-to-implement scintigraphic method that enables the assay of thyroid iodine uptake with improved accuracy and without the use of a reference source was developed with an aim to avoid unnecessary high radiation burden to patients undergoing (131)I treatment for benign thyroid disease. "
01/01/2010 - "Radioactive iodine has been used effectively in the diagnosis and treatment of thyroid diseases. "
09/01/2013 - "Therefore, the iodine status in women needs to be improved and screening for thyroid disease should be performed early in pregnancy. "
02/01/2010 - "In a cross-sectional study, we aimed to determine the influence of parity in combination with other risk factors on the prevalence of goitre and nodular thyroid disease (NTD) in women living in a region of previous overt iodine deficiency, which experienced a continuous improvement in alimentary iodine supply in the last two decades. "

12/01/1979 - "In view of the past contradictory reports concerning in vitro lymphocyte transformation induced by human thyroglobulin (Tg) in thyroid diseases, the present study was undertaken to re-examine the response using improved methods in cell separation, culture, and cell harvesting. "
09/01/2015 - "The aim of the present study was to detect thyroglobulin (Tg) gene polymorphisms in a Han Chinese population from the Northern regions of Henan province, China, and to study the correlation between Tg gene polymorphisms and autoimmune thyroid disease (AITD). "
06/01/2008 - "This study was performed to identify the presence of previously reported thyroglobulin (Tg) gene single nucleotide polymorphisms (SNPs) in Han Chinese Asians, and to investigate their potential relation to autoimmune thyroid disease (AITD). "
07/01/2004 - "Recent linkage and association studies provide evidence for thyroglobulin (Tg) being an autoimmune thyroid disease (AITD) susceptibility gene. "
08/01/2000 - "AIM of this study is to evaluate new and controversially discussed indications for determining the thyroglobulin (Tg) level in different thyroid diseases to support routine diagnostics. "

09/01/1989 - "The assay allows improved precision in establishing replacement and suppressive doses of hormone for thyroid disease."
10/01/1997 - "Cigarette smoking has been linked to thyroid disease, although studies of this problem have not shown consistent affects, with some studies linking smoking to increased thyroid hormone levels, and others to decreased thyroid hormone levels. "
06/01/1959 - "[Value of the determination of the thyrotropic hormone in the blood for the study of the physiopathology of thyroid diseases]."
02/01/2015 - "Anti-Müllerian hormone as a marker of premature ovarian aging in autoimmune thyroid disease."
01/01/2015 - "We attempted to identify the serum hCG level that causes GTT, and we compared the serum hCG levels and thyroid hormone levels of GTT patients according to whether they had a background of thyroid disease. "

12/01/2003 - "In this review we discuss the various methods to evaluate therapeutic efficacy and bioequivalence of levothyroxine preparations in the treatment of thyroid disease. "
12/01/2003 - "Evaluation of the therapeutic efficacy of different levothyroxine preparations in the treatment of human thyroid disease."
10/01/2013 - "In this study, we examined the associations between the concentrations of free thyroxine (FT4) and TSH and all-cause mortality in older men without thyroid disease. "
09/01/2013 - "Appropriately powered large-scale clinical trials analyzing the risks vs benefits of treating subclinical thyroid disease are required to determine whether these benefits can be achieved with levothyroxine therapy."
01/01/2008 - "Whether the increase in carotid IMT is due to thyroxine ingestion or underlying thyroid disease cannot be answered from the study."

08/01/2014 - "A study of IgG4 autoantibody levels in juvenile thyroid disease patients showed evidence of heritability using the ROMP screening method. "
11/01/2005 - "Putative association between anti-Borrelia IgG and autoimmune thyroid disease?"
11/01/2002 - "The specificity of enriched TPO-specific IgG+ memory B cells was confirmed by in vitro proliferation and differentiation into antibody-secreting cells at limiting dilution and analysis of the supernatants for the presence of TPO-specific IgG. Detection of TPO-specific IgG+ memory B cells in most patients with clinically manifested autoimmune thyroid disease and few normal blood donors may argue for a role of circulating memory B cells in onset of disease."
11/01/2002 - "Autoreactive IgG+ memory B cells were found in 65% of the patients with autoimmune thyroid disease and in 17% of normal blood donors; 40% of the latter had no detectable TPO-specific IgG in the serum. "
01/01/2001 - "The prevalence of platelet-associated IgG (paIgG) in nonthrombocytopenic patients with autoimmune thyroid disease (AITD) alone or associated with autoimmune polyglandular syndrome (APS) has been studied. "

05/01/1999 - "We suggest a serological screening for coeliac disease in all patients with autoimmune thyroid disease measuring anti-endomysial antibodies, considering that early detection and treatment of coeliac disease are effective in preventing its complications."
10/01/2013 - "Future studies should examine TSH changes specifically in certain "at-risk" sub-groups such as those with antibodies and known thyroid disease."
02/01/2012 - "While a positive association exists between the presence of anti-thyroid antibodies and increased pregnancy loss, universal screening of all pregnant women for underlying autoimmune thyroid disease is difficult to justify until there is evidence of beneficial outcomes from randomised controlled trials. "
02/01/2009 - "The study identifies pendrin as a novel autoantigen recognized by patients with autoimmune thyroid diseases and proposes the use of pendrin antibodies as an accurate diagnostic tool."
05/01/2006 - "Recent data from large population studies have suggested a much lower TSH cut-off with an upper limit of 2-2.5 mU/l but application of strict criteria for inclusion of subjects from the general population studies aiming at assessing TSH reference intervals (no personal or family history of thyroid disease, no thyroid antibodies and a normal thyroid on ultrasonography) did not result in an unequivocal upper limit of normal TSH at 2.0-2.5 mU/l. "

04/01/2013 - "Levels of other autoantibodies and Igs do not correlate with the development of thyroid disease in these patients, and thyroid disease does not appear to affect the efficacy of Peg-IFN + RBV antiviral therapy."
11/01/2010 - "The aim of this study was to estimate the diagnostic sensitivity of thyroid autoantibodies in individuals with a case-mix of subjects with thyroid disease representing that of the general population. "
09/01/2010 - "Based on the results of our study, we suggest that thyroid diseases of a mother might participate in congenital malformations of their newborn, although no direct association between thyroid autoantibodies and congenital malformations has been described as of yet."
05/01/1996 - "In this study we searched for thyroid disease and thyroid autoantibodies in patients with TS. "
05/01/1991 - "Because of potential bias in this study which was carried out in families with autoimmune thyroid disease (AITD), the inheritance of thyroid autoantibodies has been evaluated in 49 families unselected for autoimmune thyroid disease. "

01/01/2014 - "This study evaluated women's thyroid disease symptoms, physical findings, stress levels, and thyroid stimulating hormone (TSH) levels across six postpartum months in three groups, TPO negative, TPO positive, and PPT positive women. "
07/01/2011 - "A retrospective review of patients with thyroid disease followed by a prospective observational study in consecutive patients with newly found suppressed serum thyrotrophin (TSH). "
03/01/2010 - "The aim of this study was to assess whether serum thyroid-stimulating hormone (TSH) levels are of value in predicting malignancy in patients with nodular thyroid disease (NTD). "
12/01/1998 - "Evaluation of highly sensitive thyrotropin assay for detecting thyroid diseases in neonatal screening: preliminary studies."
01/14/1989 - "[Study of thyroid function parameters and thyrotropin in general non-thyroid diseases]."

03/01/2013 - "Future studies should focus on discovering the immunogenetic overlap between autoimmune thyroid diseases and PAH: common human leukocyte antigen alleles, susceptibility loci and so on. "
10/01/2012 - "This study aims to investigate the association of human leukocyte antigen (HLA) class II genes and cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) with autoimmune thyroid diseases in the Lebanese population. "
04/01/2011 - "Only few data exist on genetic associations of APS type 2. In this controlled study, 98 patients with APS type 2, 96 patients with type 1 diabetes (T1D), and 92 patients with autoimmune thyroid disease, both as a single autoimmune endocrinopathy, were tested for association with alleles of the human leukocyte antigen (HLA) class II loci DRB1, DQA1, and DQB1. "
01/15/2006 - "Although many studies have been carried out on TPO since it was first identified as being the thyroid microsomal antigen involved in autoimmune thyroid disease, previous authors have focused more on the immunological than on the biochemical aspects of TPO during the last few years. "
11/20/1984 - "Further studies are necessary to elucidate the antigen specific T cell function in autoimmune thyroid diseases."

01/01/2014 - "Because the TSH receptor (TSHR) plays an important role in the pathogenesis of thyroid disease, a TSHR antagonist could be a novel treatment. "
05/01/2005 - "Our previous studies using microsatellite markers near or in the TSH receptor (TSHR) gene revealed significant association between autoimmune thyroid disease (AITD) in Japanese patients and TSHR microsatellite alleles. "
01/01/2000 - "The aim of this study was the evaluation of the diagnostic and clinical impact of a new RRA (DYNOtest TRAKhuman) which uses the human recombinant TSH-Receptor in the diagnosis of autoimmune thyroid disease. "
12/01/2013 - "Targeting thyroid diseases with TSH receptor analogs."
12/01/2012 - "The thyroid-stimulating hormone receptor (TSHR) gene is a convincing candidate gene in the pathogenesis of certain thyroid diseases including MNG. "

04/01/2004 - "Near-total thyroidectomy could be the best treatment for thyroid disease in endemic regions."
12/01/2007 - "Thyroid disease is common, and thyroidectomy is a mainstay of treatment for many benign and malignant thyroid conditions. "
03/01/2012 - "The aim of this study was to assess the safety and efficacy of endoscopic thyroidectomy (ET) for bilateral thyroid diseases. "
01/01/1998 - "The goal of this study was to evaluate the safety and efficacy of total thyroidectomy performed for benign thyroid disease. "
07/01/2007 - "The identification of incidental thyroid diseases helped guide patient counselling and combined surgery with HNC and thyroidectomy. "

07/01/1986 - "Records of 38 children treated surgically at Texas Children's Hospital between 1972 and 1984 have been reviewed to determine the incidence of benign vs. malignant pathosis and to study the role of prior irradiation or chemotherapy in the pathogenesis of thyroid disease. "
11/01/2011 - "Traditional forms of treatment of the thyroid diseases: pharmacotherapy, radioiodine therapy and surgery can not always be applied. "
10/01/2005 - "Pharmacotherapy of autoimmune thyroid disease (AITD) is complex. "
05/01/2003 - "Surgery versus pharmacotherapy of benign thyroid diseases."
10/01/2002 - "Serum levels of sICAM-1 can be used as a parameter in diagnosing autoimmune thyroid disease and in evaluating the effects of therapy, drug administration or relapse in GD."

12/01/2005 - "In this prospective study, patients with pHPT (PTX) and benign euthyroid thyroid disease (THY) referred for operation were evaluated pre- and postoperatively with validated psychometric and neurocognitive instruments to determine whether learning, memory, or concentration improved with after parathyroidectomy. "
03/01/1999 - "The aim of this study was to determine the frequency of thyroid disease associated with HPT in 54 consecutive patients who underwent parathyroidectomy in our center from January 1990 to December 1997. "
09/01/2010 - "Patients were divided into three groups: those who did not have any thyroid disease, those who had concomitant TND not necessary to resect, and those in whom thyroid resection due to TND was necessary at the time of parathyroidectomy. "
11/01/2007 - "Patients who underwent surgical procedures for recurrent thyroid disease, intentional parathyroidectomy, and resection of central compartment viscera were excluded. "
10/01/2007 - "Minimally invasive parathyroidectomy is not contraindicated on the basis of cost by an inability to screen for synchronous thyroid disease. "

09/01/2010 - "In patients with benign thyroid disease, stent placement can serve as an effective bridge to surgery."
09/01/2010 - "From 1996 to 2009, covered retrievable self-expandable nitinol stents were placed in nine symptomatic patients with malignant (n=7) or benign (n=2) thyroid disease. "
09/01/2010 - "Management of tracheal obstruction caused by benign or malignant thyroid disease using covered retrievable self-expandable nitinol stents."
09/01/2010 - "Placement of covered retrievable self-expandable nitinol stents was safe and effective in patients with airway obstruction caused by benign or malignant thyroid disease. "
09/01/2010 - "To evaluate the safety and clinical effectiveness of covered retrievable self-expandable nitinol stents placed in patients with airway obstruction caused by benign or malignant thyroid disease. "

05/01/1999 - "Animal models with experimentally induced or spontaneously developed autoimmune thyroid disease as well as transplantation models have been used extensively in these studies, but also the use of thyroid cell cultures from both humans and animals has contributed to the present state of knowledge. "
01/01/1987 - "Transplantation of human endocrine tissues to nude mice: a suitable in vivo model for the study of pathomechanisms involved in autoimmune thyroid diseases."
01/01/1981 - "Transplantation of human thyroid tissue might be a useful model for studies of thyroid diseases."
01/13/2011 - "Subject 2 developed autoimmune thyroid disease 1.6 years after transplantation. "
01/01/2009 - "Autoimmune thyroid disease occurs in some complete DiGeorge anomaly patients after thymus transplantation. "