Abstract | OBJECTIVE: DESIGN: Laboratory study. SETTING: University-affiliated laboratory. PATIENT(S): INTERVENTION(S): Cells were treated with tranilast (300 μM) for 48 hours to measure extracellular matrix and activin-A expression by real-time reverse-transcription polymerase chain reaction and/or immunocytochemistry. MAIN OUTCOME MEASURE(S): RESULT(S): CONCLUSION(S):
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Authors | Md Soriful Islam, Olga Protic, Andrea Ciavattini, Stefano Raffaele Giannubilo, Andrea Luigi Tranquilli, William H Catherino, Mario Castellucci, Pasquapina Ciarmela |
Journal | Fertility and sterility
(Fertil Steril)
Vol. 102
Issue 2
Pg. 597-606
(Aug 2014)
ISSN: 1556-5653 [Electronic] United States |
PMID | 24934492
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved. |
Chemical References |
- Anti-Allergic Agents
- Collagen Type I
- Collagen Type I, alpha 1 Chain
- Fibronectins
- RNA, Messenger
- VCAN protein, human
- activin A
- ortho-Aminobenzoates
- Activins
- Versicans
- tranilast
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Topics |
- Activins
(metabolism)
- Administration, Oral
- Adult
- Anti-Allergic Agents
(administration & dosage, pharmacology)
- Cell Line, Tumor
- Collagen Type I
(genetics, metabolism)
- Collagen Type I, alpha 1 Chain
- Extracellular Matrix
(genetics, metabolism)
- Female
- Fibronectins
(genetics, metabolism)
- Fibrosis
- Humans
- Leiomyoma
(genetics, metabolism, pathology)
- Middle Aged
- Myometrium
(drug effects, metabolism, pathology)
- RNA, Messenger
(metabolism)
- Tumor Cells, Cultured
- Uterine Neoplasms
(genetics, metabolism, pathology)
- Versicans
(genetics, metabolism)
- ortho-Aminobenzoates
(administration & dosage, pharmacology)
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