Abstract | BACKGROUND: Intramedullary spinal cord metastasis (ISCM) is an uncommon complication of malignancy. ISCM from thyroid cancer is extremely rare, only a few cases had been reported and most were found at autopsy. Here we report a patient with progressive lower leg weakness due to ISCM from papillary thyroid carcinoma who had a good response to surgery. PATIENT FINDINGS: A 44-year-old woman presented with bilateral lower leg pain in December 2009. She underwent a total thyroidectomy in 1997 because of large mass in the right neck, which was diagnosed as papillary thyroid carcinoma. She had repeated I-131 therapies, but brain metastasis developed in 2002. When she was admitted, lower leg pain and weakness progressed rapidly. We performed magnetic resonance of the spine and whole-body fluorodeoxyglucose (FDG)-positron emission tomography scan, which demonstrated a 2×6 cm intramedullary mass enhanced by gadolinium with FDG-uptake. She underwent emergency laminotomy with subtotal tumor removal. Pathology revealed metastatic papillary thyroid carcinoma. After the emergent operation she could walk without help. CONCLUSION:
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Authors | Min Ji Jeon, Tae Yong Kim, Ji Min Han, Ji Hye Yim, Seung Chul Rhim, Won Bae Kim, Young Kee Shong |
Journal | Thyroid : official journal of the American Thyroid Association
(Thyroid)
Vol. 21
Issue 11
Pg. 1269-71
(Nov 2011)
ISSN: 1557-9077 [Electronic] United States |
PMID | 21936676
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Iodine Radioisotopes
- Radiopharmaceuticals
- Fluorodeoxyglucose F18
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Topics |
- Adult
- Carcinoma
- Carcinoma, Papillary
- Female
- Fluorodeoxyglucose F18
- Humans
- Iodine Radioisotopes
(therapeutic use)
- Laminectomy
(methods)
- Leg
(physiopathology)
- Magnetic Resonance Imaging
- Positron-Emission Tomography
(methods)
- Radiopharmaceuticals
- Spinal Cord Neoplasms
(diagnosis, radiotherapy, secondary, surgery)
- Thyroid Cancer, Papillary
- Thyroid Neoplasms
(pathology, radiotherapy, secondary, surgery)
- Thyroidectomy
- Treatment Outcome
- Walking
- Whole Body Imaging
(methods)
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