Abstract | OBJECTIVE: METHODS: One hundred overt hypothyroid patients, 100 subclinical hypothyroid patients and 200 healthy controls enroled in this study. The Third Adult Treatment Panel of the National Cholesterol Education Program (NCEP- ATP III) criteria were used for metabolic syndrome diagnosis. RESULTS: Body mass index was similar among the groups. Waist circumference was lower in the control group than in the hypothyroid patients (p=0.0001). Homeostasis model assessment (HOMA) insulin resistance was higher in the hypothyroid group than in the control (p=0.008) and subclinical hypothyroid (p=0.014) groups. Metabolic syndrome prevalence was 44% in the hypothyroid group, 35% in the subclinical hypothyroid group and 33% in the control group (p=0.016 for the hypothyroid group vs controls and p=0.002 for the hypothyroid group vs subclinical hypothyroid group). Waist circumference was larger in the hypothyroid metabolic syndrome patients than in the subclinical hypothyroid group and controls (p=0.001). Blood glucose, lipid parameters and blood pressure were similar among the groups. CONCLUSIONS:
|
Authors | M Erdogan, A Canataroglu, S Ganidagli, M Kulaksızoglu |
Journal | Journal of endocrinological investigation
(J Endocrinol Invest)
2011 Jul-Aug
Vol. 34
Issue 7
Pg. 488-92
ISSN: 1720-8386 [Electronic] Italy |
PMID | 20651468
(Publication Type: Journal Article)
|
Chemical References |
|
Topics |
- Adult
- Body Mass Index
- Comorbidity
- Female
- Humans
- Hypothyroidism
(blood, diagnosis, epidemiology, physiopathology)
- Male
- Metabolic Syndrome
(blood, diagnosis, epidemiology, physiopathology)
- Middle Aged
- Triglycerides
(blood)
- Waist Circumference
- Young Adult
|