Abstract | BACKGROUND: STUDY DESIGN: A randomized, double-blind, equivalence trial. SETTING: An interventional pain management practice, a specialty referral center, a private practice setting in the United States. OBJECTIVES: METHODS: OUTCOMES ASSESSMENT: Multiple outcome measures were utilized which included the Numeric Rating Scale (NRS), the Oswestry Disability Index 2.0 (ODI), employment status, and opioid intake with assessment at 3 months, 6 months, and 12 months post-treatment. Significant pain relief was defined as 50% or more, whereas significant improvement in disability score was defined as reduction of 40% or more. RESULTS: Significant pain relief (> or =50%) was demonstrated in 55% to 65% of the patients and functional status improvement with 40% reduction in ODI scores in 55% to 80% of the patients. The overall average procedures per year were 3.4 +/- 1.27 in Group I and 2.6 +/- 1.35 in Group II with an average total relief per year of 30.3 +/- 19.49 weeks in Group I and 23.1 +/- 21.36 weeks in Group II over a period of 52 weeks. LIMITATIONS: The results of this study are limited by the lack of a placebo group and a preliminary report of 20 patients in each group, even though sample was justified. CONCLUSION:
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Authors | Laxmaiah Manchikanti, Kimberly A Cash, Carla D McManus, Vidyasagar Pampati, Salahadin Abdi |
Journal | Pain physician
(Pain Physician)
2008 Nov-Dec
Vol. 11
Issue 6
Pg. 833-48
ISSN: 1533-3159 [Print] United States |
PMID | 19057629
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
- Anesthetics, Local
- Drug Combinations
- Steroids
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Topics |
- Adult
- Aged
- Anesthetics, Local
(administration & dosage)
- Chronic Disease
(drug therapy)
- Disability Evaluation
- Double-Blind Method
- Drug Combinations
- Female
- Fluoroscopy
(methods, statistics & numerical data)
- Humans
- Injections, Epidural
(methods, statistics & numerical data)
- Low Back Pain
(drug therapy, etiology, physiopathology)
- Male
- Middle Aged
- Nerve Block
(methods, statistics & numerical data)
- Pain Measurement
- Spinal Stenosis
(complications, drug therapy, physiopathology)
- Steroids
(administration & dosage)
- Treatment Outcome
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