Abstract | BACKGROUND: METHODS: A total of 31 patients, who were admitted for craniotomy, were enrolled into this study. After the operation, the patients were divided into three groups. Group I consisted of 9 patients with postoperative hypertensive crisis, and group II was composed of 13 patients without postoperative hypertensive crisis. Nine patients, who denied history of hypertension or HICH, were set as group III. The levels of some vasoactivators in the three groups were measured before and after the operation. The differences in the results among the groups were analyzed using the ANOVA. The data collected before and after the operation in the group I was compared by Wilcoxon test. RESULTS: The concentration of endothelin in group I was significantly higher than that in group III (P < 0.05). The level of thromboxane A2 and the ratio of thromboxane B2 to 6-keto-PGF1a in group I were significantly higher than those in the other two groups (P < 0.05). In group I, the levels of plasma renin activity, angiotensin II, aldosterone, catecholamine, and endothelin before the operation were significantly higher than those determined after the operation (P > 0.05). CONCLUSIONS:
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Authors | Zhi Wang, Xue-feng Wang, Chao Wang, Wen-zhong Luan |
Journal | Chinese medical journal
(Chin Med J (Engl))
Vol. 120
Issue 23
Pg. 2129-31
(Dec 05 2007)
ISSN: 0366-6999 [Print] China |
PMID | 18167188
(Publication Type: Journal Article)
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Chemical References |
- Endothelins
- Thromboxane B2
- 6-Ketoprostaglandin F1 alpha
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Topics |
- 6-Ketoprostaglandin F1 alpha
(blood)
- Adult
- Aged
- Endothelins
(blood)
- Female
- Humans
- Hypertension
(blood, etiology)
- Intracranial Hemorrhage, Hypertensive
(blood, physiopathology, surgery)
- Male
- Middle Aged
- Postoperative Complications
(blood)
- Thromboxane B2
(blood)
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