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Epoprostenol (Prostacyclin)

A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).
Also Known As:
Prostacyclin; Epoprostenol Sodium; Flolan; Epoprostanol; Epoprostenol Sodium Salt, (5Z,9alpha,11alpha,13E,15S)-Isomer; Prostaglandin I(2); Veletri; Prostaglandin I2; Prosta-5,13-dien-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (5Z,9alpha,11alpha,13E,15S)-
Networked: 4670 relevant articles (339 outcomes, 529 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Sitbon, Olivier: 31 articles (01/2021 - 02/2002)
2. Sakai, Yoshiki: 26 articles (12/2021 - 12/2005)
3. Humbert, Marc: 24 articles (12/2019 - 02/2002)
4. Simonneau, Gérald: 23 articles (01/2021 - 06/2002)
5. Rubin, Lewis J: 22 articles (01/2021 - 03/2002)
6. Barst, Robyn J: 21 articles (02/2015 - 03/2002)
7. Matsubara, Hiromi: 19 articles (11/2019 - 10/2004)
8. Farber, Harrison W: 18 articles (04/2022 - 12/2005)
9. Satoh, Toru: 18 articles (01/2022 - 12/2003)
10. McLaughlin, Vallerie V: 18 articles (01/2021 - 09/2002)

Related Diseases

1. Pulmonary Hypertension
2. Pulmonary Arterial Hypertension
3. Familial Primary Pulmonary Hypertension
4. Hypoxia (Hypoxemia)
5. Thrombosis (Thrombus)

Related Drugs and Biologics

1. Epoprostenol (Prostacyclin)
2. Iloprost (Ventavis)
3. Vasodilator Agents (Vasodilators)
4. Nitric Oxide (Nitrogen Monoxide)
5. treprostinil
6. Thromboxanes
7. beraprost
8. Aspirin (Acetylsalicylic Acid)
9. Sildenafil Citrate (Viagra)
10. Thromboxane A2 (A2, Thromboxane)

Related Therapies and Procedures

1. Therapeutics
2. Intravenous Infusions
3. Surgical Amputation (Amputations)
4. Aftercare (After-Treatment)
5. Transplantation