Abstract | PURPOSE OF REVIEW: To review recent studies on the immune-mediated pathogenesis of abdominal aortic aneurysms, opening a wide field for possible new therapeutic approaches. RECENT FINDINGS: SUMMARY: Pathophysiological, immunogenetical and interventional studies support the concept of abdominal aortic aneurysm as an immune-mediated process, which will help to identify more laboratory and imaging signs of development in the future. Further research will now assess the possible benefit of antiinflammatory therapeutic approaches, especially in patients with small abdominal aortic aneurysms.
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Authors | Michael Schirmer, Christina Duftner, Ruediger Seiler, Christian Dejaco, Gustav Fraedrich |
Journal | Current opinion in rheumatology
(Curr Opin Rheumatol)
Vol. 18
Issue 1
Pg. 48-53
(Jan 2006)
ISSN: 1040-8711 [Print] United States |
PMID | 16344619
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
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Topics |
- Aortic Aneurysm, Abdominal
(diagnosis, immunology, physiopathology)
- Arteritis
(complications, immunology)
- Humans
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