Abstract | BACKGROUND AND OBJECTIVES: METHODS: Seventy outpatients undergoing knee arthroscopy were blindly randomized to receive either 100 mg hyperbaric procaine or 50 mg hyperbaric lidocaine. An interview by a blinded investigator established the presence or absence of TNS, defined as pain in the buttocks or lower extremities beginning within 24 hours of surgery. Onset of sensory and motor block, patient discomfort, supplemental anesthetics, and side effects were recorded by the unblinded managing anesthesia team. Anesthetic adequacy was determined from these data by a single blinded investigator. Hospital discharge time was recorded from the patient record. Groups were compared using appropriate statistics with a P < .05 considered significant. RESULTS:
TNS occurred in 6% of procaine patients versus 31% of lidocaine patients (P = .007). Sensory block with procaine and lidocaine was similar, while motor block was decreased with procaine (P < .05). A trend toward a higher rate of block inadequacy (17% v 3%, P = .11) and intraoperative nausea (17% v 3%, P = .11) occurred with procaine. Average hospital discharge time with procaine was increased by 29 minutes (P < .05). CONCLUSIONS:
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Authors | P S Hodgson, S S Liu, M S Batra, T W Gras, J E Pollock, J M Neal |
Journal | Regional anesthesia and pain medicine
(Reg Anesth Pain Med)
2000 May-Jun
Vol. 25
Issue 3
Pg. 218-22
ISSN: 1098-7339 [Print] England |
PMID | 10834773
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Anesthetics, Local
- Procaine
- Lidocaine
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Topics |
- Ambulatory Surgical Procedures
- Anesthesia, Spinal
(adverse effects)
- Anesthetics, Local
(adverse effects)
- Arthroscopy
- Double-Blind Method
- Female
- Humans
- Knee
(surgery)
- Leg
(surgery)
- Lidocaine
(adverse effects)
- Male
- Middle Aged
- Neurotoxicity Syndromes
(physiopathology, prevention & control)
- Procaine
(adverse effects)
- Prospective Studies
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