Surgical Blood Loss

01/01/2014 - "Among other prevention methods, treatment with tranexamic acid (ATX) has shown to be effective in reducing surgical blood loss, especially in the immediate postoperative period. "
09/01/2012 - "The antifibrinolytic tranexamic acid reduces surgical blood loss, but studies have not identified an optimal regimen. "
06/01/2015 - "Tranexamic Acid Tamponade to Control Postoperative Surgical Hemorrhage."
01/01/2015 - "Tranexamic acid for the prevention and management of orthopedic surgical hemorrhage: current evidence."
09/01/2013 - "Systematic review, meta-analysis and meta-regression of the effect of tranexamic acid on surgical blood loss."

09/01/2011 - "This clinical study aimed to test the hypothesis that SpHb monitoring was equivalent to that of HemoCue® (the automated hemoglobin measurement in the laboratory taken as a reference method) during acute surgical hemorrhage. "
06/01/2014 - "In multilevel models adjusted for comorbidities, surgical service, estimated surgical blood loss, and lowest in-hospital hemoglobin value, with surgeon and procedure as random effects, patients > 65 years old had 62% greater odds (odds ratio, 1.62; 95% confidence interval, 1.40-1.88; P < 0.0001) of being transfused than did younger patients. "
06/01/2014 - "The primary analysis compared the odds of transfusion for patients >65 years old with the odds of transfusion in younger patients based on multilevel multivariable logistic regression analyses including adjustment for comorbidities, surgical service, lowest in-hospital hemoglobin value, gender, and estimated surgical blood loss and accounted for clustering by the surgeon and procedure. "
12/01/2013 - "There was no difference in age, gender, body mass index (BMI), number of dissected lymph node, levels of hemoglobin and albumin at admission, intraoperative hemorrhage, surgical duration and pathological TNM stage in two groups (all P > 0.05). "
07/21/2005 - "The changes of the intraoperative CVP, surgical blood loss, blood products used and the changes of perioperative hemoglobin (Hb) between groups were analyzed and compared by using Mann-Whitney U test. "

05/01/2008 - "However, a low CVP may not be tolerated by all patients: intraoperative hemodynamic instability may, in fact, easily ensue because of the cardiovascular depressant effects of anesthetics, surgical blood losses, and manipulation of the inferior vena cava. "
11/01/2001 - "Many alternative medicines may interact with anesthetic drugs to inhibit coagulation, precipitating unnecessary surgical blood loss. "
01/01/1974 - "Effect of anesthetics on surgical blood loss."
02/01/1970 - "Surgical blood loss associated with various anesthetics."
03/01/1999 - "In our study, surgical blood loss was the same for both anesthetic agents overall, but propofol appeared to offer an advantage in terms of subjective improvement in operating conditions, particularly in the ethmoid and sphenoid sinuses."

03/01/1999 - "In our study, surgical blood loss was the same for both anesthetic agents overall, but propofol appeared to offer an advantage in terms of subjective improvement in operating conditions, particularly in the ethmoid and sphenoid sinuses."
01/01/2001 - "We conclude that maintenance of anaesthesia with propofol TCI at 2-5 microg ml(-1) does not cause detectable coagulation changes on thrombelastography nor increase surgical blood loss when compared to inhaled isoflurane."

02/01/2009 - "Hydroxyethyl starch 130/0.4 and surgical blood loss."
10/01/2003 - "Hydroxyethyl starch solutions (HES) are increasingly used for the compensation of surgical blood loss. "
11/01/2001 - "To compare the tolerance and efficacy of the new hydroxyethyl starch (HES) 130/0.4 with a current HES solution (HES 200/0.5) in patients undergoing preoperative autologous blood donation as a model of surgical blood loss. "
05/01/1987 - "We conclude that dextran and hydroxyethyl starch can be used safely in a dose of 20 ml/kg in component therapy of surgical blood loss, provided that haematocrit is kept at an acceptable level, attention is paid to the postoperative hypoproteinaemia, and the patient has a normal haemostatic function preoperatively."
05/01/1987 - "The safety of plasma expanders, hydroxyethyl starch 120 and dextran 70, administered in the highest recommended doses (20 ml/kg) as adjuncts of component therapy of surgical blood loss was studied in patients undergoing major abdominal surgery and compared with a group receiving 4% albumin solution for initial haemodilution and whole blood for further blood loss replacement. "

04/15/2015 - "The antifibrinolytics TXA and EACA have been shown to improve hemostasis in large blood loss surgical procedures. "
01/01/2010 - "Systemic antifibrinolytic agents are widely used in surgery to prevent clot breakdown (fibrinolysis) in order to reduce surgical blood loss. "
03/01/2010 - "This article provides an overview of the scientific evidence regarding the efficacy and safety of antifibrinolytic agents and desmopressin to reduce surgical blood loss. "

04/01/2015 - "The antifibrinolytic, tranexamic acid (TXA), is a lysine analog that inhibits activation of plasminogen and has shown to be beneficial in reducing surgical blood loss. "

04/01/2015 - "The antifibrinolytic, tranexamic acid (TXA), is a lysine analog that inhibits activation of plasminogen and has shown to be beneficial in reducing surgical blood loss. "

11/01/2001 - "To compare the tolerance and efficacy of the new hydroxyethyl starch (HES) 130/0.4 with a current HES solution (HES 200/0.5) in patients undergoing preoperative autologous blood donation as a model of surgical blood loss. "

12/21/2009 - "We found the best hemoglobin correlations were when ratios at isosbestic points of oxy- and deoxyhemoglobin were used, specifically 529/500 nm. Baseline subtraction improved correlations, specifically at 520/509 nm. These results demonstrate proof-of-concept for the ability of this noninvasive device to monitor hemoglobin concentration changes due to surgical blood loss. "

03/01/2006 - "The aim of this study was to evaluate the effect of neuraxial blocks on surgical blood losses and on the number of patients requiring blood transfusion. "
09/01/2015 - "The main outcome measures were duration of ambulance transfer, RTS, blood loss, surgical procedures, and blood transfusions. "
06/01/2014 - "Although blood transfusion is a common therapeutic intervention and a mainstay of treating surgical blood loss, it may be perceived by patients and their physicians as having associated risk of adverse events. "
04/01/2012 - "Large variation exists in hospitals' intraoperative blood transfusion practices for older patients with significant surgical blood loss. "
04/01/2012 - "Association between hospital intraoperative blood transfusion practices for surgical blood loss and hospital surgical mortality rates."

09/01/2007 - "Mean surgical blood loss was 313 ml, which was significantly less than in those undergoing open cystectomy (588 ml). "
02/01/2009 - "ANH may be effective in reducing the necessity of allogenic blood transfusion during radical cystectomy with a relatively large surgical blood loss."
09/01/2001 - "The mean volume of surgical blood loss was 1,659 ml ranging from 529 to 2,990 ml in total cystectomy, and 1,438 ml ranging from 553 to 2,841 ml in radical prostatectomy. "
01/01/2000 - "The volume of surgical blood loss were 381 +/- 522 ml in nephrectomy (1,158 +/- 202 ml in bilateral case), 517 +/- 5 ml in radical nephro-ureterectomy 636 +/- 574 ml in RPLND, 665 +/- 291 ml in radical prostatectomy and 1,123 +/- 417 ml in radical cystectomy. "

07/01/1976 - "SNP has been found predictable and effective in reducing surgical blood loss in selected patients undergoing total hip replacement."
03/01/2006 - "In summary neuraxial blocks have a clear and definite effect on surgical blood loss, but this effect do not usually lead to a reduction in the number of transfused patients except for patients undergoing total hip replacement and spinal fusion."

12/01/2008 - "Preoperative uterine artery embolization with resorbable agents was effective in reducing surgical blood losses. "

03/01/2001 - "Perioperative factors that correlated with the decreased death rate over time were the increased postoperative use of epidural analgesia and bronchoscopy (for clearance of pulmonary secretions), a decrease in history of smoking, and a decrease in surgical blood loss of more than 1,000 mL. In this series of predominantly transthoracic esophagectomies, there has been a decline in the hospital death rate to less than 5%. "