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Oral Contraceptives

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Compounds, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy. The hormones are generally estrogen or progesterone or both.

Also Known As:

Contraceptives, Oral; Oral Contraceptives, Low-Dose; Oral Contraceptives, Phasic; Contraceptives, Low-Dose Oral; Contraceptives, Phasic Oral; Low-Dose Oral Contraceptives; Oral Contraceptives, Low Dose; Phasic Oral Contraceptives

Networked: 5070 relevant articles (156 outcomes, 544 trials/studies)

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Bio-Agent Context: Research Results

Experts

1.	Rosendaal, F R: 19 articles (09/2015 - 01/2000)
2.	Rosendaal, Frits R: 18 articles (01/2014 - 05/2002)
3.	Helmerhorst, F M: 15 articles (04/2014 - 01/2000)
4.	Bioulac-Sage, Paulette: 11 articles (04/2015 - 03/2003)
5.	Maia, Hugo: 11 articles (01/2014 - 02/2006)
6.	Rosing, J: 10 articles (11/2014 - 07/2000)
7.	Malone, Kathleen E: 10 articles (08/2014 - 06/2002)
8.	Jick, Susan S: 10 articles (07/2014 - 09/2005)
9.	La Vecchia, Carlo: 10 articles (03/2014 - 02/2002)
10.	Lopez, Laureen M: 10 articles (01/2014 - 01/2008)

Related Diseases

1.	Acne Vulgaris 05/01/2008 - "Oral contraceptives (OCs) have been shown to be safe and effective for the treatment of acne in most women of childbearing potential, and several have been approved by the Food and Drug Administration for this purpose. " 11/01/1997 - "Because oral contraceptives (OCs) may reduce the active androgen level, hormonal therapy with OCs has been used successfully to treat patients with acne, although this treatment has previously not been studied in placebo-controlled trials. " 01/01/2004 - "In women, acne can be successfully treated with oral contraceptives. " 07/01/2002 - "As shown in several pilot and in multiple open and comparative studies, oral contraceptives (OCs) are effective in causing a significant regression of mild to moderate acne. " 01/01/2004 - "Recent controlled clinical trials have demonstrated the efficacy of various hormonal preparations, including oral contraceptives, in treatment of acne. "
2.	Ovarian Neoplasms (Ovarian Cancer) 06/01/2013 - "Prevention options include the use of oral contraceptives, which are known to be highly effective for decreasing risk of both endometrial and ovarian cancer in the general population, and prophylactic surgery to remove the uterus and ovaries. " 04/01/2013 - "Ever use of oral contraceptives was also protective against ovarian cancer; adjusted OR 0.56 (95% CI, 0.40 to 0.78). " 10/01/2001 - "Oral contraceptives have been shown to be protective against hereditary ovarian cancer. " 11/20/2001 - "Our study provides evidence that low-dose oral contraceptives confer substantial protection against the development of ovarian cancer." 03/05/2008 - "Use of oral contraceptives can explain reduced incidence of ovarian cancer in Sweden]."
3.	Endometriosis (Adenomyosis) 01/01/2014 - "We compared the efficacy of postoperative use of LNG-IUS with oral contraceptives (OC) for preventing endometrioma recurrence. " 10/01/2013 - "The primary aim of the study was to analyze the endometrioma recurrence rate in patients who underwent laparoscopic excision followed by postoperative long-term regimen of oral contraceptives (OCs). " 12/01/2009 - "The aim of this study was to evaluate the impact of post-operative oral contraceptives (OCs) use on the rate of recurrence after laparoscopic excision of ovarian endometrioma. " 09/01/2000 - "In a prospective, randomized trial 70 patients who were not attempting to conceive, aged 20 to 35 years, underwent laparoscopic excision of ovarian endometriomas, followed by either postoperative administration of low-dose cyclic oral contraceptives for 6 months or no treatment on the basis of a computer-generated sequence. " 01/01/2000 - "The search strategy of the Menstrual Disorders Group was utilised to identify all randomised trials of the use of oral contraceptives in the treatment of symptomatic endometriosis. "
4.	Ovarian Cysts (Ovarian Cyst) 11/01/2014 - "Oral contraceptives are not an effective treatment for ovarian cysts." 12/01/2000 - "In conclusion, expectant management is as effective as oral contraceptives for the resolution of functional ovarian cysts induced by ovarian stimulation. " 01/01/2014 - "We included randomized controlled trials in any language that included oral contraceptives used for treatment and not prevention of functional ovarian cysts. " 01/01/2014 - "This review examined all randomized controlled trials that studied oral contraceptives as therapy for functional ovarian cysts. " 01/01/2011 - "We included randomized controlled trials in any language that included oral contraceptives used for treatment and not prevention of functional ovarian cysts. "
5.	Hirsutism 09/01/2008 - "Today, for the majority of women, a monotherapy with oral contraceptives that have antiandrogenic activity is recommended as a first-line treatment for hirsutism. " 05/01/2003 - "Efficacy of second versus third generation oral contraceptives in the treatment of hirsutism." 11/01/1991 - "A treatment to keep hirsutism in remission while minimizing lipid disturbances was attempted in 20 formerly hirsute patients with hirsutism scores already greatly reduced after oral contraceptives (OCs) treatment. " 01/01/2013 - "Management of clinical manifestations of PCOS includes oral contraceptives for menstrual irregularities and hirsutism. " 07/01/2010 - "Over a 15-year period spanning from January 1991 to January 2006, a total of 414 premenopausal women with hirsutism of different aetiopathogeneses received yearly reducing doses (250, 125 and 62.5 mg/day) of Flu alone or in combination with oral contraceptives for a period varying from at least 3 to 8 years and more. "

Related Drugs and Biologics

1.	Estrogens (Estrogen)
2.	Progestins (Progestagens)
3.	Androgen Antagonists (Antiandrogens)
4.	Aromatase (CYP19)
5.	Hormones
6.	Gonadotropin-Releasing Hormone (GnRH)
7.	Metformin (Glucophage)
8.	Levonorgestrel (Plan B)
9.	Gestodene
10.	drospirenone

Related Therapies and Procedures

1.	Contraception (Birth Control)
2.	Hormone Replacement Therapy (Therapy, Hormone Replacement)
3.	Tubal Sterilization (Tubal Ligation)
4.	Injections
5.	Condoms (Condom)