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S 15511
a therapeutic metabolite of the insulin-sensitizing agent S 15261
Networked:
1
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Fluorenes: 7
S 15511: 1
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Fluorenes: 7
S 15511: 1
Experts
1.
Pickavance, L C
: 1 article (01/2007)
2.
Wilding, J P H
: 1 article (01/2007)
Related Diseases
1.
Insulin Resistance
01/01/2007 - "
Deterioration in insulin sensitivity [homeostasis model assessment (HOMA)-IR: + 239%; p < 0.01] was attenuated by S 15511, S 15511 + Y 415 and pair-feeding (p < 0.01) and was compensated for by improved insulin secretion (HOMA-beta; p < 0.01).
"
01/01/2007 - "
The mechanism of action of S 15511 may be via increased insulin sensitivity and beta-cell response preservation up to day 21.
"
2.
Weight Gain
01/01/2007 - "
S 15511 alone and combined with Y 415 reduced energy intake and weight gain (-13% vs. controls; both p < 0.01).
"