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Jelleine I

an antimicrobial peptide from the Royal Jelly of honeybees (Apis mellifera)

Also Known As:

PFKLSLHL-NH(2)

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 84029
  - Oligopeptides: 527
    - Jelleine I: 5

Experts

1.	Jia, Fengjing: 2 articles (01/2023 - 03/2021)
2.	Brito, Julio Cesar Moreira: 1 article (01/2024)
3.	Lima, Maria Elena de: 1 article (01/2024)
4.	Lima, William Gustavo: 1 article (01/2024)
5.	Verly, Rodrigo Moreira: 1 article (01/2024)
6.	Dang, Xiangli: 1 article (02/2023)
7.	Ding, Kang: 1 article (02/2023)
8.	Huang, Xiuhong: 1 article (02/2023)
9.	Shen, Panpan: 1 article (02/2023)
10.	Tian, Jinhuan: 1 article (02/2023)

Related Diseases

1.	Colorectal Neoplasms (Colorectal Cancer) 01/11/2023 - "Optimized Antimicrobial Peptide Jelleine-I Derivative Br-J-I Inhibits Fusobacterium Nucleatum to Suppress Colorectal Cancer Progression."
2.	Peritonitis 03/01/2021 - "In addition, the result of in vivo antimicrobial activity experiment showed that Jelleine-I performed a good therapeutic effect toward the mice with Escherichia coli infected peritonitis. "
3.	Neoplasms (Cancer) 01/01/2024 - "Jelleine-I, but not the other analogues, also has antiparasitic, healing, and pro-coagulant activities in addition to indirectly modulating tumor cell growth and controlling the inflammatory process. "
4.	Melanoma (Melanoma, Malignant) 05/01/2020 - "Aiming a deeper understanding, we chose the octapeptide Jelleine-I (JI) for its selective and low toxicity profile, designed small modifications combining the substitutions of Phe by Trp and Lys/His by Arg and tested the antimicrobial and anticancer activity on melanoma cells. "
5.	Hemolysis 02/16/2023 - "Furthermore, Jelleine-I increased the G1 to S phase transition in mammalian cells from cells cycle analysis, and cytotoxicity assay results indicated that it promoted cell proliferation without hemolysis or cytotoxicity. "

Related Drugs and Biologics

1.	Therapeutic Uses
2.	Cytokines
3.	Interleukin-6 (Interleukin 6)
4.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
5.	Coagulants
6.	Antiparasitic Agents (Antiparasitics)
7.	Adenosine Monophosphate (AMP)
8.	Antimicrobial Peptides
9.	gloverin
10.	Hyalophora cecropia cecropin D protein

Related Therapies and Procedures

1.	Immunomodulation