N-succinimidyl-4-fluorobenzoate

used to label proteins with F(18); structure in first source; RN refers to 18F-labeled isomer

Also Known As:

(18F)SFB; N-succinimidyl 4-(18F)fluorobenzoate; N-succinimidyl 4-fluorobenzoate; N-succinimidyl-4-(18F)fluorobenzoate; NSM-FB

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

1.	Abousekhrah, A: 1 article (03/2021)
2.	Al Jammaz, I: 1 article (03/2021)
3.	Al-Malki, Y: 1 article (03/2021)
4.	Al-Otaibi, B: 1 article (03/2021)
5.	Okarvi, S M: 1 article (03/2021)
6.	Chen, Supin: 1 article (10/2019)
7.	Collins, Jeffrey: 1 article (10/2019)
8.	Javed, Muhammad Rashed: 1 article (10/2019)
9.	Keng, Pei Yuin: 1 article (10/2019)
10.	Kim, Chang-Jin C J: 1 article (10/2019)

1.	Prostatic Neoplasms (Prostate Cancer) 10/07/2019 - "A small-animal immunoPET pilot study demonstrated that the [18F]SFB-PSCA diabody conjugate showed specific uptake in the PSCA-positive human prostate cancer xenograft. "
2.	Neoplasms (Cancer) 03/18/2021 - "Biodistribution in SCID mice bearing MCF7 xenografts, demonstrated excellent tumor uptake (12% ID/g) and favorable kinetics for MUC1-FA-[18F] SFB over MUC1-[18F]SFB. " 03/18/2021 - "These results demonstrate that MUC1-FA-[18F] SFB may be a useful PET imaging probe for breast cancer detection and monitoring tumor response to the treatment."
3.	Melanoma (Melanoma, Malignant) 01/01/2018 - "For the development of radiotracers that enable PET imaging of the melanoma-associated lysyl oxidase activity, substrates derived from the type I collagen α1 N-telopeptide were labeled with fluorine-18 using N-succinimidyl 4-[18F]fluorobenzoate ([18F]SFB) as prosthetic reagent. "
4.	Breast Neoplasms (Breast Cancer) 03/18/2021 - "These results demonstrate that MUC1-FA-[18F] SFB may be a useful PET imaging probe for breast cancer detection and monitoring tumor response to the treatment."

1.	Collagen Type I (Type I Collagen)
2.	Protein-Lysine 6-Oxidase (Lysyl Oxidase)
3.	Indicators and Reagents (Reagents)
4.	collagen type I trimeric cross-linked peptide
5.	Fluorine-18