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10-hydroxy-cis-12-octadecenoic acid

linoleic acid metabolite produced by gut lactic acid bacterium Lactobacillus plantarum

Networked: 5 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - Monounsaturated Fatty Acids: 676
      - Oleic Acids: 67
        10-hydroxy-cis-12-octadecenoic acid: 5

Experts

1.	Kishino, Shigenobu: 3 articles (01/2019 - 06/2015)
2.	Ogawa, Jun: 3 articles (01/2019 - 06/2015)
3.	Miyamoto, Junki: 2 articles (01/2019 - 12/2017)
4.	Kitamura, Nahoko: 2 articles (12/2017 - 06/2015)
5.	Park, Si-Bum: 2 articles (12/2017 - 06/2015)
6.	Sulijaya, Benso: 1 article (04/2020)
7.	Takahashi, Naoki: 1 article (04/2020)
8.	Yamazaki, Kazuhisa: 1 article (04/2020)
9.	Arita, Makoto: 1 article (01/2019)
10.	Drucker, Daniel J: 1 article (01/2019)

Related Diseases

1.	Periodontal Diseases (Periodontal Disease) 04/29/2020 - "Recent studies have focused on the protective function of poly unsaturated fatty acids, 10-oxo-trans-11-oxadecenoic acid (KetoC) and 10-hydroxy-cis-12-octadecenoic acid (HYA), generated by gut microbiota on periodontal disease. "
2.	Atopic Dermatitis (Atopic Eczema) 12/01/2017 - "Supplemental feeding of a gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, alleviates spontaneous atopic dermatitis and modulates intestinal microbiota in NC/nga mice." 12/01/2017 - "The present study investigated the antiallergic and anti-inflammatory effects of 10-hydroxy-cis-12-octadecenoic acid (HYA), a novel gut microbial metabolite of linoleic acid, in NC/Nga mice, a model of atopic dermatitis (AD). "
3.	Inflammation (Inflammations) 01/01/2019 - "The recent discovery of novel dietary ω3 and ω6 lipid-derived metabolites-such as resolvin, protectin, maresin, 17,18-epoxy-eicosatetraenoic acid and microbe-dependent 10-hydroxy-cis-12-octadecenoic acid-and their potent biologic effects on the regulation of inflammation have initiated a new era of nutritional immunology. " 01/01/2019 - "Supplementation of 10-hydroxy-cis-12-octadecenoic acid (HYA), an initial linoleic acid-related gut-microbial metabolite, attenuates HFD-induced obesity in mice without eliciting arachidonic acid-mediated adipose inflammation and by improving metabolic condition via free fatty acid receptors. "
4.	Obesity 01/01/2019 - "Supplementation of 10-hydroxy-cis-12-octadecenoic acid (HYA), an initial linoleic acid-related gut-microbial metabolite, attenuates HFD-induced obesity in mice without eliciting arachidonic acid-mediated adipose inflammation and by improving metabolic condition via free fatty acid receptors. "
5.	Dehydration (Water Stress) 06/01/2015 - "The maximal activities for the hydration of linoleic acid and for the dehydration of 10-hydroxy-cis-12-octadecenoic acid (HYA) were observed at 37 °C in buffer at pH 5.5 containing 0.5 M NaCl. "

Related Drugs and Biologics

1.	Linoleic Acid (Linoleate)
2.	Acids
3.	Anti-Allergic Agents (Antiallergic Agents)
4.	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)
5.	CD59 Antigens
6.	Arachidonic Acid (Vitamin F)
7.	Lipids
8.	Nonesterified Fatty Acids (NEFA)
9.	Buffers