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ceragenin CSA-131

prevents formation of bacterial and fungal biofilms on endotracheal tubes

Also Known As:

CSA-131

Networked: 9 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - ceragenin CSA-131: 9

Experts

1.	Savage, Paul B: 7 articles (10/2021 - 01/2018)
2.	Bozkurt-Guzel, Cagla: 3 articles (01/2021 - 08/2018)
3.	Bucki, Robert: 2 articles (10/2021 - 01/2020)
4.	Piktel, Ewelina: 2 articles (10/2021 - 01/2020)
5.	Deng, Shenglou: 2 articles (03/2018 - 01/2018)
6.	Hashemi, Marjan M: 2 articles (03/2018 - 01/2018)
7.	Hilton, Brian: 2 articles (03/2018 - 01/2018)
8.	Holden, Brett S: 2 articles (03/2018 - 01/2018)
9.	Taylor, Maddison F: 2 articles (03/2018 - 01/2018)
10.	Wilson, John: 2 articles (03/2018 - 01/2018)

Related Diseases

1.	Infections 08/24/2023 - "CSA-44 and CSA-131 alone/or in combinations with MEM or CZA can be considered as new alternative treatments in serious infections caused by MDR pathogens." 03/07/2018 - "These findings suggest that CSA-131, formulated in micelles, may act as a potential therapeutic for polymicrobial and biofilm-related infections in the lung and trachea." 08/01/2020 - "According to the results, CSA-13 and CSA-131 can be good alternatives for infections caused by carbapenem-resistant A. " 01/01/2021 - "In vitro assessment of CSA-131 and CSA-131 poloxamer form for the treatment of Stenotrophomonas maltophilia infections in cystic fibrosis."
2.	Neoplasms (Cancer) 10/29/2021 - "Administration of CSA-131 and AuP@CSA-131 prevented the inflammatory response associated with cancer development. " 01/01/2023 - "Erratum: Quantification of Synergistic Effects of Ceragenin CSA-131 Combined with Iron Oxide Magnetic Nanoparticles Against Cancer Cells [Corrigendum]." 01/01/2020 - "Quantification of Synergistic Effects of Ceragenin CSA-131 Combined with Iron Oxide Magnetic Nanoparticles Against Cancer Cells." 10/29/2021 - "Peanut-Shaped Gold Nanoparticles with Shells of Ceragenin CSA-131 Display the Ability to Inhibit Ovarian Cancer Growth In Vitro and in a Tumor Xenograft Model."
3.	Ovarian Neoplasms (Ovarian Cancer) 10/29/2021 - "In vivo efficiency of intravenously and intratumorally administered CSA-131 and AuP@CSA-131 was examined using a xenograft ovarian cancer model. " 10/29/2021 - "For the purpose of toxicity/efficiency ratio control, peanut-shaped gold nanoparticles (AuP NPs) were functionalized with a shell of ceragenin CSA-131 and the cytotoxicity of AuP@CSA-131 against ovarian cancer SKOV-3 cells and were then analyzed. " 10/29/2021 - "Peanut-Shaped Gold Nanoparticles with Shells of Ceragenin CSA-131 Display the Ability to Inhibit Ovarian Cancer Growth In Vitro and in a Tumor Xenograft Model."
4.	Mycoses (Diseases, Fungus) 01/01/2018 - "Gel and cream formulations including 2% CSA-44 or CSA-131 resulted in reductions of over 4 logs against established fungal infections in ex vivo mucosal tissues. "
5.	Cystic Fibrosis (Mucoviscidosis) 01/01/2021 - "In vitro assessment of CSA-131 and CSA-131 poloxamer form for the treatment of Stenotrophomonas maltophilia infections in cystic fibrosis."

Related Drugs and Biologics

1.	Micelles
2.	ferric oxide (iron oxide)
3.	Poloxamer (Poloxamer 407)
4.	Carbapenems (Carbapenem Antibiotics)
5.	Gold