Immunoglobulin Variable Region

That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions.

Also Known As:

Framework Region, Immunoglobulin; Fv Antibody Fragments; Fv Fragments; Ig Framework Region; Ig Variable Region; Immunoglobulin Framework Region; Immunoglobulin Fv Fragments; Immunoglobulin V; Antibody Fragment, Fv; Antibody Fragments, Fv; Fragment, Fv; Fragment, Fv Antibody; Fragment, Immunoglobulin Fv; Fragments, Fv; Fragments, Fv Antibody; Fragments, Immunoglobulin Fv; Framework Region, Ig; Framework Regions, Ig; Framework Regions, Immunoglobulin; Fv Antibody Fragment; Fv Fragment; Fv Fragment, Immunoglobulin; Fv Fragments, Immunoglobulin; Ig Framework Regions; Ig Variable Regions; Immunoglobulin Framework Regions; Immunoglobulin Fv Fragment; Immunoglobulin Variable Regions; Regions, Immunoglobulin Variable; Variable Regions, Ig; Variable Regions, Immunoglobulin; Variable Region, Ig; Variable Region, Immunoglobulin

Pharmalogical Action Categories:

Immunologic Factors

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Immunoglobulin Fragments: 976
        Immunoglobulin Fab Fragments: 769
        Immunoglobulin Variable Region: 208
        Immunoglobulin Variable Region: 208
    - Immunoproteins: 43
      - Immunoglobulins: 30480
        Immunoglobulin Fragments: 976
        Immunoglobulin Fab Fragments: 769
        Immunoglobulin Variable Region: 208
        Immunoglobulin Variable Region: 208
  - Globulins: 3062
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Immunoglobulin Fragments: 976
        Immunoglobulin Fab Fragments: 769
        Immunoglobulin Variable Region: 208
        Immunoglobulin Variable Region: 208
- Peptides: 82426
  - Peptide Fragments: 373
    - Immunoglobulin Fragments: 976
      - Immunoglobulin Fab Fragments: 769
        Immunoglobulin Variable Region: 208
Chemical Phenomena
- Biochemical Phenomena
  - Molecular Structure
    - Amino Acid Sequence
      - Immunoglobulin Variable Region: 208

4D5scFv-miniSOG immunophototoxin

Bio-Agent Context: Research Results