Blood Proteins (Serum Proteins)

06/01/2005 - "Intravenously injected PS undergo a transition from being bound to serum proteins, then bound to endothelial cells, then bound to the adventitia of the vessels, then bound either to the extracellular matrix or to the cells within the tumor, and finally to being cleared from the tumor by lymphatics or blood vessels, and excreted either by the kidneys or the liver. "
01/01/1983 - "Corticosteroid therapy reduced the water content of peritumoral brain tissue but did not affect increased barrier permeability of tumor vessels, and only slightly improved peritumoral accumulation of serum proteins. "
11/01/2014 - "The results of this study demonstrate that the quantitative analysis of a panel of serum proteins can detect the presence of early intestinal tumors in a rat model, and provides support for future measurements in humans."
01/01/2010 - "Recent progress in proteomics studies which profiled the serum proteins of cancer patients and those of normal individuals indicated that the altered APRP expressions were different for distinct types, subtypes, and even stages of cancer. "
04/28/2007 - "Proteomic studies of mouse models of cancer allow assessment of the range of changes in plasma proteins that occur with tumor development and may lead to the identification of potential cancer markers applicable to humans."

08/01/1972 - "The present study was directed toward determining the role of the kidney in the metabolism of various classes of serum proteins and to define the urinary protein excretion patterns and the pathogenesis of disorders of protein metabolism in patients with proteinuria. "
05/01/2013 - "In addition, understanding the sieving process is a prerequisite to understanding the pathogenesis of proteinuria (that is, the leakage of plasma proteins into the urine). "
05/01/2005 - "Proteinuria is the consequence of glomerular filtration of plasma proteins, their subsequent reabsorption by the proximal tubular cells and secretion of protein by the tubular cells and distal urinary tract. "
11/01/2004 - "It has been proposed that filtration of potentially tubulotoxic plasma proteins is responsible for the observed correlations between proteinuria and progression (i.e., proteinuria is a cause and not only a consequence of progressive renal injury). "
02/01/2002 - "These are the first data demonstrating permeability activity for serum proteins, an observation with important implications in pathogenesis of proteinuria. "

08/01/2000 - "In this model of acute lung injury, the intra-alveolar repletion of surfactant components in early recovery led to improved surfactant function despite the presence of potentially inhibitory plasma proteins."
03/01/2012 - "Dietary plasma proteins attenuate the innate immunity response in a mouse model of acute lung injury."
07/19/2000 - "Acute lung injury results in surfactant dysfunction due in part to inhibition by serum proteins. "
08/01/1996 - "Thus, plasma proteins decrease the threshold at which endotoxin primes the lung and may have a critical role in the pathogenesis of endotoxin-induced acute lung injury."
10/01/1992 - "These findings suggest that the alveolar fluid after acute lung injury possesses enhanced antioxidant activity that is likely due to the influx of serum proteins. "

01/01/2009 - "Because screening mammography for breast cancer is less effective for premenopausal women, we investigated the feasibility of a diagnostic blood test using serum proteins. "
05/01/2013 - "This analysis was conducted to identify plasma proteins associated with CRFS in disease-free breast cancer patients. "
04/15/2012 - "In this study, we sought to identify coordinated changes in plasma proteins associated with breast cancer based on large-scale quantitative mass spectrometry. "
11/01/2010 - "Applying advanced proteomic technologies to prospectively collected specimens from large studies is one means of identifying preclinical changes in plasma proteins that are potentially relevant to the early detection of diseases such as breast cancer. "
08/01/2009 - "In the present study, a two-dimensional liquid chromatography-tandem mass spectrometry (2D-LC-MS/MS) on a linear ion trap was utilized to identify and compare serum proteins from breast cancer patients. "

05/01/1993 - "The wound chamber method employed in the present study may provide a useful model for investigations dealing with the roles of circulating plasma proteins and other molecules as well as local cellular products involved in wound healing and nerve regeneration."
11/01/2004 - "In all species the basic mechanism of clot formation is similar; when endothelium is damaged a complex sequence of enzymatic reactions occurs that is localized to the site of trauma and involves both activated cells and plasma proteins. "
01/01/2001 - "[Early evaluation of blood loss by the profile of blood proteins in patients with injuries]."
06/19/1999 - "Because we found no evidence of T cell infiltration accompanying the exudates, our results indicate that in the absence of physical trauma or inflammatory cells resident CNS neuroglia remain quiescent upon exposure to extravasated serum proteins."
10/01/1996 - "[Changes in cell membrane lipid composition when exposed to native plasma proteins during thermal trauma]."