Verrucous Carcinoma
165
relevant articles (7 outcomes,
14 trials/studies)
found for this Disease
Description:
A variant of well-differentiated epidermoid carcinoma that is most common in the oral cavity, but also occurs in the larynx, nasal cavity, esophagus, penis, anorectal region, vulva, vagina, uterine cervix, and skin, especially on the sole of the foot. Most intraoral cases occur in elderly male abusers of smokeless tobacco. The treatment is surgical resection. Radiotherapy is not indicated, as up to 30% treated with radiation become highly aggressive within six months. (Segen, Dictionary of Modern Medicine, 1992)
Also Known As:
Carcinoma, Verrucous; Carcinomas, Verrucous; Verrucous Carcinomas
Relationship Network
Disease Context: Research Results
Related Diseases
Experts
| 1. | Sheen, Maw-Chang:
3 articles
(05/2008 - 06/2003)
|
| 2. | Wu, Chih-Fung:
3 articles
(05/2008 - 06/2003)
|
| 3. | Sheu, Hamm-Ming:
2 articles
(07/2005 - 06/2003)
|
| 4. | Wang, Yi-Wen:
2 articles
(07/2005 - 06/2003)
|
| 5. | Chai, Chee-Yin:
2 articles
(07/2005 - 06/2003)
|
| 6. | Chen, Chung-Ming:
1 article
(05/2008)
|
| 7. | Chen, Chung-Ho:
1 article
(05/2008)
|
| 8. | Shen, Yee-Shyong:
1 article
(05/2008)
|
| 9. | Shieh, Tien-Yu:
1 article
(05/2008)
|
| 10. | Chen, Ching-Yi:
1 article
(05/2008)
|
Drugs and Biologics
Drugs and Important Biological Agents (IBA) related to Verrucous Carcinoma:
| 1. | 1-phenyl-3,3-dimethyltriazene (PDT)IBA
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| 2. | Bleomycin (Blenoxane)FDA LinkGeneric
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| 3. | InterferonsIBA
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| 4. | Fluorouracil (Carac)FDA LinkGeneric
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| 5. | DNA (Deoxyribonucleic Acid)IBA
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| 6. | ParaffinIBA
03/01/2005
- " METHODS: In the present study, 36 paraffin-embedded betel-associated oral carcinoma samples including 27 squamous cell carcinoma (SCC) and nine verrucous carcinomas (VC) were analyzed for the hypermethylation of tumor suppressor genes (TSGs) and loss of heterozygosity (LOH) of important TSG loci" 12/01/2002
- " METHODS:Randomly selecting achieved paraffin blocks, including 60 cases of squamous cell carcinoma(SCC), 30 cases of verrucous carcinoma(VC) of oral mucosa and 30 cases of basal cell carcinoma (BCC) of epidermis" 12/01/2002
- " METHODS: Randomly selecting achieved paraffin blocks, including 60 cases of squamous cell carcinoma(SCC), 30 cases of verrucous carcinoma(VC) of oral mucosa and 30 cases of basal cell carcinoma(BCC) of epidermis" 06/01/2005
- " The study materials consisted of representative formalin-fixed and paraffin-embedded tissue blocks from 19 cases of verrucous carcinoma, 18 classic squamous cell carcinoma, and 14 squamous epithelial hyperplasia (acanthosis)" 12/01/1995
- " We studied p53 over-expression in a series of 42 primary penile carcinomas (seven verrucous carcinomas, 14 well-differentiated, 15 moderately-differentiated and six poorly-differentiated squamous cell carcinomas) from Chinese patients using the p53 protein specific mouse monoclonal antibody DO-7 on paraffin sections"
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| 7. | Proteins (Proteins, Gene)IBA
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| 8. | Formaldehyde (Formol)IBA
06/01/2005
- " The study materials consisted of representative formalin-fixed and paraffin-embedded tissue blocks from 19 cases of verrucous carcinoma, 18 classic squamous cell carcinoma, and 14 squamous epithelial hyperplasia (acanthosis)" 03/01/1998
- " HPV DNA in situ hybridization for HPV Types 6/11, 16/18, and 31/33/35 was performed on formalin-fixed, paraffin-embedded tissue from six cases of verrucous carcinoma and four cases of condyloma acuminatum in perianal specimens from HIV-seropositive patients" 08/01/1996
- " The incidence of p53 antigen and human papillomavirus (HPV) expression in archival formalin-fixed, paraffin-embedded tissue sections from verrucous carcinoma of the larynx was determined using immunohistochemistry" 04/01/1993
- " The incidence of human papillomavirus (HPV) DNA in archival formalin-fixed, paraffin-embedded tissue sections from verrucous carcinoma of the larynx was determined using polymerase chain reaction (PCR) with consensus primers and by in situ hybridization designed to detect HPV types 6/11, 16/18, 31/33/35" 08/01/1995
- " Silver-binding nucleolar-organizer regions (AgNORs) were counted in sections from formalin-fixed, paraffin-embedded blocks of 24 cases of well-differentiated squamous cell carcinoma, 6 cases of verrucous carcinoma, and 11 cases of normal oral mucosa"
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| 9. | AntibodiesIBA
04/01/2005
- " STUDY DESIGN: In a direct enzyme-linked immunosorbent assay, serum samples from 126 healthy control subjects, 97 women with lichen sclerosus with or without squamous hyperplasia, 78 women with vulvar intraepithelial neoplasia, and 16 women with verrucous carcinoma were examined for immunoglobulin G and A antibodies to L1 virus-like particles of genital human papillomavirus types 6, 11, 16, 18, and 31, cutaneous human papillomavirus type 8, bovine papilloma virus, and cottontail rabbit papilloma virus" 08/01/1995
- " The expression and localization of glutathione S-transferase (GST) isoenzymes in the epithelium of normal oral mucosa (n = 9), overlying reactive fibrous hyperplasia (n = 9), and of potentially malignant [leukoplakia (n = 25), submucous fibrosis (n = 12), verrucous hyperplasia (n = 16)] and malignant [squamous cell carcinoma (n = 36), verrucous carcinoma (n = 13)] oral lesions were examined immunohistochemically using polyclonal antibodies raised against GST isoenzymes (alpha, mu and pi) with the standard avidin-biotin-peroxidase complex (ABC) method"
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| 10. | moesinIBA
05/01/1998
- " Verrucous carcinoma was weakly positive, with a tendency for the moesin to be distributed in the cell membrane" 07/01/2003
- " The purpose of the study is to assess the shifts in cellular distribution of moesin in normal oral epithelium, oral epithelial dysplasia (OED), verrucous carcinoma (VC), and oral squamous cell carcinoma (OSCC)" 07/01/2003
- " Shifts in cellular localization of moesin in normal oral epithelium, oral epithelial dysplasia, verrucous carcinoma and oral squamous cell carcinoma." 05/01/1998
- " Using immunohistochemistry we investigated the expression of moesin in normal epidermis and various kinds of epithelial skin tumors: squamous cell carcinoma, verrucous carcinoma, Bowen's disease, solar keratosis, keratoacanthoma, basal cell carcinoma, and extramammary Paget's disease"
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| 73 Drugs and Important Bio-Agents
and
127
more articles analyzed in the Research Interface, order at left...
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Therapies and Procedures
| 1. | Drug Therapy (Chemotherapy)
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| 2. | Amputation
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| 3. | Photochemotherapy (Photodynamic Therapy)
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| 4. | Oral Surgery (Maxillofacial Surgery)
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| 5. | Male Circumcision (Circumcision)
09/01/1995
- " We analyzed 42 cases of invasive squamous cell carcinoma, 13 of carcinoma in situ, 12 of penile intraepithelial neoplasia, 3 of verrucous carcinoma and 25 of balanitis xerotica obliterans, as well as 29 routine neonatal circumcision specimens and 32 adult circumcision specimens" 09/01/1995
- " RESULTS: Overall, the detection rates for human papillomavirus DNA in the study and control tissues were 55% (23 of 42 cases) for invasive squamous cell carcinoma, 92% (12 of 13) for carcinoma in situ, 92% (11 of 12) for penile intraepithelial neoplasia, 0% (0 of 3) for verrucous carcinoma, 4% (1 of 25) for balanitis xerotica obliterans, 0% (0 of 29) for neonatal circumcision and 9% (3 of 32) for adult circumcision"
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| 19 Therapies and Procedures
and
48
more articles analyzed in the Research Interface, order at left...
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