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Verrucous Carcinoma

A variant of well-differentiated epidermoid carcinoma that is most common in the oral cavity, but also occurs in the larynx, nasal cavity, esophagus, penis, anorectal region, vulva, vagina, uterine cervix, and skin, especially on the sole of the foot. Most intraoral cases occur in elderly male abusers of smokeless tobacco. The treatment is surgical resection. Radiotherapy is not indicated, as up to 30% treated with radiation become highly aggressive within six months. (Segen, Dictionary of Modern Medicine, 1992)
Also Known As:
Carcinoma, Verrucous; Carcinomas, Verrucous; Verrucous Carcinomas
Networked: 301 relevant articles (16 outcomes, 31 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Squamous Cell Carcinoma (Epidermoid Carcinoma)
2. Squamous Cell Carcinoma of Head and Neck
3. Hyperplasia
4. Neoplasms (Cancer)
5. Carcinoma (Carcinomatosis)

Experts

1. Sheen, Maw-Chang: 5 articles (08/2014 - 06/2003)
2. Wu, Chih-Fung: 5 articles (06/2010 - 06/2003)
3. Sheu, Hamm-Ming: 4 articles (08/2014 - 06/2003)
4. Chen, Hsin-Ming: 3 articles (05/2014 - 04/2005)
5. Berney, Daniel M: 3 articles (06/2012 - 09/2008)
6. Stankiewicz, Elzbieta: 3 articles (06/2012 - 09/2008)
7. Chiang, Chun-Pin: 3 articles (03/2011 - 04/2005)
8. Chai, Chee-Yin: 3 articles (05/2010 - 06/2003)
9. Wang, Yi-Wen: 3 articles (05/2010 - 06/2003)
10. Chung, Hong: 2 articles (01/2021 - 07/2017)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Verrucous Carcinoma:
1. 1-phenyl-3,3-dimethyltriazene (PDT)IBA
2. AcitretinFDA Link
3. Aminolevulinic Acid (Levulan)FDA Link
4. Bleomycin (Blenoxane)FDA LinkGeneric
5. InterferonsIBA
6. Fluorouracil (Carac)FDA LinkGeneric
7. Superoxide DismutaseIBA
8. RetinoidsIBA
9. Glutathione (Reduced Glutathione)IBA
10. pembrolizumabIBA

Therapies and Procedures

1. Radiotherapy
2. Drug Therapy (Chemotherapy)
3. Photochemotherapy (Photodynamic Therapy)
4. Mohs Surgery (Mohs' Micrographic Surgery)
5. Intra-Arterial Infusions