Multiple verrucous carcinomas treated with acitretin.

Abstract

Cutaneous verrucous carcinoma is a rare variant of low-grade squamous cell carcinoma. It usually involves distal extremities and is often misdiagnosed as giant warts. Multiple cutaneous verrucous carcinomas are rare in the English-language literature. We describe a 41-year-old man with multiple verrucous plaques on both feet and ankles, as well as the left thigh. Immunohistochemical study with proliferating cell nuclear antigen revealed positive staining of the basal and suprabasal layers. The patient's condition was successfully treated with systemic acitretin.

• Authors: Yue-Zon Kuan, Hsiu-cheng Hsu, Tseng-tong Kuo, Yu-Huei Huang, Hsin-Chun Ho
• Journal: Journal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 56 Issue 2 Suppl Pg. S29-32 (Feb 2007) ISSN: 1097-6787 [Electronic] United States
• PMID: 17097363 (Publication Type: Case Reports, Journal Article)

Chemical References

• Keratolytic Agents
• Proliferating Cell Nuclear Antigen
• Acitretin

Topics

• Acitretin (therapeutic use)
• Adult
• Carcinoma, Verrucous (drug therapy, metabolism, pathology)
• Humans
• Immunohistochemistry (methods)
• Keratolytic Agents (therapeutic use)
• Leg
• Male
• Proliferating Cell Nuclear Antigen (metabolism)
• Skin Neoplasms (drug therapy, metabolism, pathology)
• Staining and Labeling