Abstract | INTRODUCTION: CASE PRESENTATION: A 31-year-old White woman experiencing psychosis presented with spontaneous, acute-onset dyskinesia induced with the withdrawal of benztropine. She had been followed in our academic outpatient clinic for medication management and intermittent psychotherapy. DISCUSSION: The pathophysiology of tardive dyskinesia is not fully understood, but several hypotheses exist, including the involvement of changes in basal ganglia neuronal systems. To our knowledge, this is the first case report to document acute-onset dyskinesia associated with the withdrawal of benztropine. CONCLUSION: his case report, which describes an atypical response to discontinuing benztropine, might offer the scientific community potential clues to better understand the pathophysiology of tardive dyskinesia.
|
Authors | Sharadhi Thalner, Himanshu Agrawal |
Journal | WMJ : official publication of the State Medical Society of Wisconsin
(WMJ)
Vol. 122
Issue 2
Pg. 143-145
(May 2023)
ISSN: 2379-3961 [Electronic] United States |
PMID | 37141483
(Publication Type: Case Reports)
|
Copyright | Copyright© Board of Regents of the University of Wisconsin System and The Medical College of Wisconsin, Inc. |
Chemical References |
- Benztropine
- Antipsychotic Agents
|
Topics |
- Female
- Humans
- Adult
- Benztropine
(adverse effects)
- Tardive Dyskinesia
(chemically induced, complications, drug therapy)
- Dyskinesia, Drug-Induced
(etiology, drug therapy)
- Antipsychotic Agents
(therapeutic use)
|