Case Report: Subacute thyroiditis after receiving inactivated SARS-CoV-2 vaccine (BBIBP-CorV).

Abstract

Background:

Subacute thyroiditis, an inflammatory disease, has been reported caused by vaccines in rare cases. In the context of the coronavirus disease 19 pandemic, various SARS-CoV-2 vaccines have been developed and may be potential triggers for subacute thyroiditis.

Case presentation:

We report a case of subacute thyroiditis 3 days after receiving the second dose of inactivated SARS-CoV-2 vaccine (BBIBP-CorV). The patient did not report a previous history of thyroid disease, upper respiratory tract infection, or COVID-19. Physical examination, laboratory testing, ultrasonography, and radioactive iodine uptake were consistent with subacute thyroiditis. During follow-up, the patient recovered from symptoms and signs, and imaging changes except for hypothyroidism, requiring an ongoing thyroxine replacement.

Conclusions:

Inactivated SARS-CoV-2 vaccine may be a causal trigger leading to subacute thyroiditis. Clinicians should be aware of subacute thyroiditis as a possible thyroid-related side effect of an inactivated SARS-CoV-2 vaccine.

• Authors: Linhua Pi, Jian Lin, Ying Zheng, Zhen Wang, Zhiguang Zhou
• Journal: Frontiers in medicine (Front Med (Lausanne)) Vol. 9 Pg. 918721 ( 2022) ISSN: 2296-858X [Print] Switzerland
• PMID: 35935798 (Publication Type: Case Reports)
• Copyright: Copyright © 2022 Pi, Lin, Zheng, Wang and Zhou.