Hepatocellular carcinoma (HCC) may be caused by hepatitis B virus (HBV)
infection. Post-
infection recovery-associated changes of HBV indicators include decreased
hepatitis B surface antigen (
HBsAg) level and increased anti-
HBsAg antibody titer. Testing to detect HBV
DNA is conducted rarely but could detect latent HBV
infection persisting after acute
infection and prompt administration of treatments to clear HBV and prevent subsequent HBV-induced HCC development. Here, we present an HCC case with an extremely high anti-
HBsAg antibody titer and latent HBV
infection.
CASE SUMMARY: CONCLUSION: A rare HCC case with high serum anti-
HBsAg antibody titer and detectable HBV
DNA resulted from untreated latent HBV
infection.