Delayed localized hypersensitivity reactions to COVID-19 mRNA vaccines: a 6-month retrospective study.

Abstract

Several individuals have developed delayed localized cutaneous vaccine reactions to the two novel mRNA Covid-19 vaccines. Clinical and histopathologic results of this case series study confirm that the localized injection-site reactions to the mRNA COVID-19 vaccines are delayed hypersensitivity reactions that, unlike immediate hypersensitivity reactions, are not a contraindication to vaccination.

• Authors: I Papadimitriou, K Bakirtzi, E Sotiriou, E Vakirlis, D Hatzibougias, D Ioannides
• Journal: Clinical and experimental dermatology (Clin Exp Dermatol) Vol. 47 Issue 1 Pg. 157-158 (Jan 2022) ISSN: 1365-2230 [Electronic] England
• PMID: 34288056 (Publication Type: Letter)
• Copyright: © 2021 British Association of Dermatologists.

Chemical References

• 2019-nCoV Vaccine mRNA-1273

Topics

• 2019-nCoV Vaccine mRNA-1273 (adverse effects)
• Adult
• Aged
• Aged, 80 and over
• COVID-19 (prevention & control)
• Drug Hypersensitivity (etiology, pathology)
• Female
• Humans
• Hypersensitivity, Delayed (chemically induced, pathology)
• Injection Site Reaction (etiology)
• Male
• Middle Aged
• Retrospective Studies
• SARS-CoV-2